CAJ | 학술논문

目的:观察不同疾病患者行眼底荧光血管造影(flourescence fundus angiography,FFA)的方法和对不良反应的防范. 方法:患者签署知情同意书后,双眼散瞳,所有病例常规行双眼裂隙灯和直接、间接眼底镜检查,拍摄双眼的彩色眼底照片,静脉注射1 %荧光素钠注射液5 mL,观察15 min,无任何不良反应后快速静脉推注10 %荧光素钠注射液4.5 mL,采用Topcon TRC-50EX眼底照相系统进行检查. 结果:2 841例患者均顺利完成造影,其中糖尿病性视网膜病变1 031 例、高血压性眼底改变530 例、视网膜静脉阻塞382例、黄斑病变162例、眼外伤113例、中心性浆液性和渗出性脉络膜视网膜病89例、变性近视眼底改变72 例、原发性视网膜色素变性68例、黄斑裂孔61例、黄斑视网膜前膜58例、血管炎55例、视网膜血管炎51例、视乳头缺血性视乳头病变38例、视网膜动脉阻塞37例、Stargardt病18例、旁中心凹视网膜毛细血管扩张症13例、其他眼病63例;23例患者转上级医院进行进一步确诊;发生不良反应132例(4.6 %),未发生严重不良反应事件. 结论:在眼底荧光血管造影检查中,临床医生要做好各项应急预防措施,根据患者的病情种类、有无合并症等制定规范的个体化拍摄计划,提高操作和诊断水平以及对不良反应的观察和处理能力,获得理想的眼底荧光血管造影图像,为眼底病的诊断、治疗提供可靠的依据.
목적:관찰불동질병환자행안저형광혈관조영(flourescence fundus angiography,FFA)적방법화대불량반응적방범. 방법:환자첨서지정동의서후,쌍안산동,소유병례상규행쌍안렬극등화직접、간접안저경검사,박섭쌍안적채색안저조편,정맥주사1 %형광소납주사액5 mL,관찰15 min,무임하불량반응후쾌속정맥추주10 %형광소납주사액4.5 mL,채용Topcon TRC-50EX안저조상계통진행검사. 결과:2 841례환자균순리완성조영,기중당뇨병성시망막병변1 031 례、고혈압성안저개변530 례、시망막정맥조새382례、황반병변162례、안외상113례、중심성장액성화삼출성맥락막시망막병89례、변성근시안저개변72 례、원발성시망막색소변성68례、황반렬공61례、황반시망막전막58례、혈관염55례、시망막혈관염51례、시유두결혈성시유두병변38례、시망막동맥조새37례、Stargardt병18례、방중심요시망막모세혈관확장증13례、기타안병63례;23례환자전상급의원진행진일보학진;발생불량반응132례(4.6 %),미발생엄중불량반응사건. 결론:재안저형광혈관조영검사중,림상의생요주호각항응급예방조시,근거환자적병정충류、유무합병증등제정규범적개체화박섭계화,제고조작화진단수평이급대불량반응적관찰화처리능력,획득이상적안저형광혈관조영도상,위안저병적진단、치료제공가고적의거.
Objective:To investigate the methods of fundus fluorescein angiography (FFA) performed in patients with different diseases and the prevention of adverse reaction.Methods:Each participant signed written informed consent.After going through mydriasis, all patients were ex-amined by slit lamp examination and indirect or direct fundus ophthalmoscope.Meanwhile, colourful eye fundus images were taken.All patients were injected sodium fluorescein (1 %) 5 mL, and observed 15 minutes, after which sodium fluorescein (10 %) 4.5 mL was injected rapidly if without any adverse reaction.And then they were examined by fundus camera system (Topcon TRC-50E).Results:2 841 cases had successfully finished examination.There were 1 031 patients with diabetic retinopathy, 530 patients with hypertension retinopathy, 382 patients with retinal vein occlusion, 162 patients with maculopathy, 113 patients with ocular trauma, 89 patients with central serous and exudative chorioretinopathy, 72 patients with fundus change of degenerative myopia, 68 patients with primary retinitis pigmentosa, 61 patients with macular hole, 58 patients with macular epiretinal membranes, 55 patients with vasculitis, 51 patients with retinal vasculitis, 38 patients with ischemic lesions of optic nerve head, 37 patients with retinal artery occlusion, 18 patients with Stargardt disease, 13 patients with retinal telangiectasis, and 63 patients with other disea-ses.23 patients transfered to upper-grade hospital for further diagnosis.The adverse reaction appeared in 132 cases with no severe adverse effect during the period.Conclusion:During fundus fluorescein angiography, each item of preventive measures of emergency need to be well -prepared for clinical doctors, and normative shooting plan tailored for individuals was established according to the types of patients'diseases, and the occur-rence of severe complications or not.Therefore, diagnostic and operation level and the ability to treat the adverse reaction will be enhanced , so as to provide the reliable guidance for acquiring the ideal image of FFA and for diagnosing and treating fundus diseases .