CAJ | 학술논문

目的：探讨磷酸三钙多孔陶瓷治疗60岁以下 FicatⅢ期非创伤性股骨头坏死(ONFH)的临床疗效。方法收集该院2006年3月至2009年7月非创伤性 FicatⅢ期 ONFH 患者41例(63髋),将患者分为两组,A 组(n=16)仅行单纯髓芯减压治疗；B 组(n=25)行髓芯减压+经股骨头颈交界开窗灯泡状病灶清除打压植骨术结合磷酸三钙多孔生物陶瓷植入。并对各临床评估指标进行观察及评估。结果A 组术后各时间点 PRI 差异无统计学意义(P >0.05)；B 组患者术后1个月 PRI 均较术前明显降低,此后,保持较稳定状态直至术后3年时轻微回升(P =0.033),术后所有时间点内,A 组 Harris 积分均明显低于 B 组；术后24个月、3、4、5年的比较表明 B 组的坏死区域较术前明显缩小,且均低于 A 组。结论PTCP 植入治疗60岁以下 FicatⅢ期非创伤性股骨头坏死疗效满意。
목적：탐토린산삼개다공도자치료60세이하 FicatⅢ기비창상성고골두배사(ONFH)적림상료효。방법수집해원2006년3월지2009년7월비창상성 FicatⅢ기 ONFH 환자41례(63관),장환자분위량조,A 조(n=16)부행단순수심감압치료；B 조(n=25)행수심감압+경고골두경교계개창등포상병조청제타압식골술결합린산삼개다공생물도자식입。병대각림상평고지표진행관찰급평고。결과A 조술후각시간점 PRI 차이무통계학의의(P >0.05)；B 조환자술후1개월 PRI 균교술전명현강저,차후,보지교은정상태직지술후3년시경미회승(P =0.033),술후소유시간점내,A 조 Harris 적분균명현저우 B 조；술후24개월、3、4、5년적비교표명 B 조적배사구역교술전명현축소,차균저우 A 조。결론PTCP 식입치료60세이하 FicatⅢ기비창상성고골두배사료효만의。
Objective To investigate the clinical efficacy of porous calcium phosphate bioceramics (PTCP)for treating stage FicatⅢ non-traumatic osteonecrosis of the femoral head(ONFH)in the patients aged below 60 years old.Methods A total of 41 patients (63 hips)with non-traumatic ONFH in our hospital from March 2006 to July 2009 were collected and divided into two groups.The group A (n=1 6)was performed the core decompression only,while the group B (n=25)was performed the core de-compression plus through the head-neck junction of the femur to opening the window light bulb shape focus debridement and impac-ting bone grafting combined with PTCP implantation.The various clinical evaluation indicators were observed and evaluated.Results No statistically significant differences in PRI were found at each time point in the group A.PRI at postoperative 1 month in the group B was significantly decreased than before operation,hereafter,the stable status was maintained and slightly risen again until postoperative 3 years(P =0.033).The Harris scores at postoperative all time points in the group A were significantly lower than those in the group B.The necrosis areas at postoperative 24 months,3,4,5 years in the group B were significantly decreased com-pared with before operation and lower than those in the group A.Conclusion PTCP implantation has satisfactory effect for the treatment of stage FicatⅢ non-traumatic ONFH in the patients aged below 60 years old.