CAJ | 학술논문

目的：探讨放疗前贫血对食管癌患者预后的影响。方法对焦作市第二人民医院5年间收治的137例食管癌放疗患者进行回顾性分析，其中放疗前贫血患者40例，放疗前无贫血患者97例，均采用三维适形放疗技术。采用生存分析评价贫血对患者预后的影响及与其他临床因素的相关性。结果无贫血患者的3、5年总生存率分别为43.6%和35.7%，贫血患者的3、5年总生存率分别为21.0%和16.4%；无贫血患者的3、5年无病生存率分别为38.5%和25.3%，贫血患者的3、5年无病生存率分别为13.1%和9.2%。Kaplan-Meier分析显示贫血和无贫血食管癌放疗患者总生存率和无病生存率差异均有统计学意义（均P＜0.05）。结论贫血是食管癌放疗患者独立于分期、性别、年龄、Karnofsky评分之外的预后因素。
목적：탐토방료전빈혈대식관암환자예후적영향。방법대초작시제이인민의원5년간수치적137례식관암방료환자진행회고성분석，기중방료전빈혈환자40례，방료전무빈혈환자97례，균채용삼유괄형방료기술。채용생존분석평개빈혈대환자예후적영향급여기타림상인소적상관성。결과무빈혈환자적3、5년총생존솔분별위43.6%화35.7%，빈혈환자적3、5년총생존솔분별위21.0%화16.4%；무빈혈환자적3、5년무병생존솔분별위38.5%화25.3%，빈혈환자적3、5년무병생존솔분별위13.1%화9.2%。Kaplan-Meier분석현시빈혈화무빈혈식관암방료환자총생존솔화무병생존솔차이균유통계학의의（균P＜0.05）。결론빈혈시식관암방료환자독립우분기、성별、년령、Karnofsky평분지외적예후인소。
Objective To analysis the prognosis of esophageal carcinoma patients with anemia before radiotherapy. Methods 137 patients with esophageal carcinoma treated with three-dimensional conformal radiation therapy (3D-CRT) in the Second Peopleˊs Hospital of Jiaozuo over the past five years were retrospectively analyzed. There were 40 patients with anemia and 97 cases without anemia before radiotherapy. The prognosis of patients with anemia and the relationship with other clinical factors were evaluated by survival analysis. Results The 3-year and 5-year overall survival (OS) rates in non-anemic group were 43.6 % and 35.7 %, respectively, and 21.0 % and 16.4 % in anemic group. The 3-year and 5-year disease-free survival (DFS) rates in non-anemic group were 38.5 % and 25.3 %, respectively, and 13.1 % and 9.2 %in anemic group. The Kaplan-Meier method showed that both 3-year and 5-year OS and DFS rates in non-anemic group were significantly higher than those in anemic group (P< 0.05). Conclusion Anemia is the independent prognostic factor for patients with esophageal carcinoma in many clinical factors.