中国耳鼻咽喉头颈外科
中國耳鼻嚥喉頭頸外科
중국이비인후두경외과
Chinese Archives of Otolaryngology-Head and Neck Surgery
2015年
9期
449-451
,共3页
陈茹%林森%陈崇喜%黄益灯
陳茹%林森%陳崇喜%黃益燈
진여%림삼%진숭희%황익등
焦虑%抑郁%药物疗法%咽喉反流性疾病%医院焦虑抑郁评分量表
焦慮%抑鬱%藥物療法%嚥喉反流性疾病%醫院焦慮抑鬱評分量錶
초필%억욱%약물요법%인후반류성질병%의원초필억욱평분량표
Anxiety%Depression%Drug Therapy%aryngopharyngeal reflux disease%hospital anxiety and depression scale
目的探讨咽喉反流性疾病(laryngopharyngeal reflux disease,LPRD)与焦虑、抑郁症状的相关性及治疗效果。方法选择2014年3~12月我院耳鼻咽喉科门诊就诊的98例LPRD患者,行医院焦虑抑郁量表(hospital anxiety and depression scale,HADS)评分,根据评分结果分为正常组56例和异常组42例,随机把异常组分为治疗组21例和对照组21例。正常组和异常对照组给予奥美拉唑胶囊治疗,异常治疗组在此基础上予支持疗法、暗示疗法、消除心理疑虑并加用氟哌噻吨美利曲辛片进行心理调节,比较3组患者的疗效。结果正常组、异常治疗组和异常对照组总有效率分别为51.79%(29/56)、66.67%(14/21)和14.29%(3/21),异常治疗组总有效率高于异常对照组,有显著性差异(χ2=11.958,P<0.05);正常组总有效率高于异常对照组,有显著性差异(χ2=8.843,P<0.05);异常治疗组总有效率高于正常组,差异无统计学意义(χ2=1.372,P>0.05)。结论LPRD部分患者存在焦虑或抑郁状态,进行个体化治疗,针对性的给予心理干预,可以提高疗效。
目的探討嚥喉反流性疾病(laryngopharyngeal reflux disease,LPRD)與焦慮、抑鬱癥狀的相關性及治療效果。方法選擇2014年3~12月我院耳鼻嚥喉科門診就診的98例LPRD患者,行醫院焦慮抑鬱量錶(hospital anxiety and depression scale,HADS)評分,根據評分結果分為正常組56例和異常組42例,隨機把異常組分為治療組21例和對照組21例。正常組和異常對照組給予奧美拉唑膠囊治療,異常治療組在此基礎上予支持療法、暗示療法、消除心理疑慮併加用氟哌噻噸美利麯辛片進行心理調節,比較3組患者的療效。結果正常組、異常治療組和異常對照組總有效率分彆為51.79%(29/56)、66.67%(14/21)和14.29%(3/21),異常治療組總有效率高于異常對照組,有顯著性差異(χ2=11.958,P<0.05);正常組總有效率高于異常對照組,有顯著性差異(χ2=8.843,P<0.05);異常治療組總有效率高于正常組,差異無統計學意義(χ2=1.372,P>0.05)。結論LPRD部分患者存在焦慮或抑鬱狀態,進行箇體化治療,針對性的給予心理榦預,可以提高療效。
목적탐토인후반류성질병(laryngopharyngeal reflux disease,LPRD)여초필、억욱증상적상관성급치료효과。방법선택2014년3~12월아원이비인후과문진취진적98례LPRD환자,행의원초필억욱량표(hospital anxiety and depression scale,HADS)평분,근거평분결과분위정상조56례화이상조42례,수궤파이상조분위치료조21례화대조조21례。정상조화이상대조조급여오미랍서효낭치료,이상치료조재차기출상여지지요법、암시요법、소제심리의필병가용불고새둔미리곡신편진행심리조절,비교3조환자적료효。결과정상조、이상치료조화이상대조조총유효솔분별위51.79%(29/56)、66.67%(14/21)화14.29%(3/21),이상치료조총유효솔고우이상대조조,유현저성차이(χ2=11.958,P<0.05);정상조총유효솔고우이상대조조,유현저성차이(χ2=8.843,P<0.05);이상치료조총유효솔고우정상조,차이무통계학의의(χ2=1.372,P>0.05)。결론LPRD부분환자존재초필혹억욱상태,진행개체화치료,침대성적급여심리간예,가이제고료효。
[ABSTRACT]OBJECTIVETo observe the correlation of laryngopharyngeal reflux disease(LPRD) with anxiety and depression symptoms, and to study the treatment efficacy.METHODSThe clinical data of 98 cases with LPRD were retrospectively analyzed from March 2014 to December 2014. According to the result of the Hospital Anxiety and Depression Scale(HADS) scores, 56 cases were normal and 42 cases were abnormal. The abnormal group were randomly divided into treatment group(21 cases) and control group(21cases).The control group and normal HADS group were treated by omeprazole capsules, treatment group was given omeprazole capsules and flupenthixol melitracen tablets with psychological adjustment.RESULTS The effective rate of treatment group and control group was 66.67% and 14.29% respectively, the difference was statistically significant(χ2=11.958,P<0.05). The difference between the normal HADS group and the control group also was significant(χ2=8.843,P<0.05). The difference between the normal HADS group and the treatment group was not significant(χ2=1.372,P>0.05).CONCLUSION Laryngopharyngeal reflux in some patients exist state of anxiety or depression. Individualized treatment in patients with laryngopharyngeal reflux can improve the efficacy.