CAJ | 학술논문

目的评估用Epley手法复位联合眩晕宁治疗青年后半规管良性阵发性位置性眩晕的效果.方法选择青年后半规管良性阵发性位置性眩晕患者258例(18岁≤年龄≤50岁)为研究对象,采用随机数字表随机分为单纯手法复位组86例、甲磺酸倍他司汀组86例、眩晕宁组86例.单纯手法复位组采用Epley手法复位加安慰剂,2片/次,3次/d,疗程为1个月,随访1个月.倍他司汀组和眩晕宁组在Epley手法复位的基础上分别联用倍他司汀片(12 mg/次,3次/d)或眩晕宁片(2片/次,3次/d),疗程均为1个月.结果 258例患者经过1次治疗,治愈199例,其中单纯手法复位组治愈68例,倍他司汀组治愈66例,眩晕宁组治愈65例,3组比较差异无统计学意义(x2=0.308,P＞0.05).治疗并随访1个月后,单纯手法复位组治愈72例,有效3例,无效11例;倍他司汀组治愈74例,有效3例,无效9例;眩晕宁组治愈81例,有效4例,无效1例;倍他司汀组、单纯手法复位组、眩晕宁组有效率分别为89.5％、87.2％、98.8％,3组有效率比较差异有统计学意义(x2=58.65,P＜0.05),眩晕宁组高于其他两组(P均＜0.05),而倍他司汀组和单纯手法复位组比较差异无统计学意义(P＞0.05).结论 Epley手法复位的基础上联合使用眩晕宁治疗青年后半规管良性阵发性位置性眩晕的效果优于单纯Epley手法复位及手法复位联合甲磺酸倍他司汀,而Epley手法复位联合甲磺酸倍他司汀的效果并不优于单纯手法复位.
목적 평고용Epley수법복위연합현훈저치료청년후반규관량성진발성위치성현훈적효과.방법 선택청년후반규관량성진발성위치성현훈환자258례(18세≤년령≤50세)위연구대상,채용수궤수자표수궤분위단순수법복위조86례、갑광산배타사정조86례、현훈저조86례.단순수법복위조채용Epley수법복위가안위제,2편/차,3차/d,료정위1개월,수방1개월.배타사정조화현훈저조재Epley수법복위적기출상분별련용배타사정편(12 mg/차,3차/d)혹현훈저편(2편/차,3차/d),료정균위1개월.결과 258례환자경과1차치료,치유199례,기중단순수법복위조치유68례,배타사정조치유66례,현훈저조치유65례,3조비교차이무통계학의의(x2=0.308,P＞0.05).치료병수방1개월후,단순수법복위조치유72례,유효3례,무효11례;배타사정조치유74례,유효3례,무효9례;현훈저조치유81례,유효4례,무효1례;배타사정조、단순수법복위조、현훈저조유효솔분별위89.5％、87.2％、98.8％,3조유효솔비교차이유통계학의의(x2=58.65,P＜0.05),현훈저조고우기타량조(P균＜0.05),이배타사정조화단순수법복위조비교차이무통계학의의(P＞0.05).결론 Epley수법복위적기출상연합사용현훈저치료청년후반규관량성진발성위치성현훈적효과우우단순Epley수법복위급수법복위연합갑광산배타사정,이Epley수법복위연합갑광산배타사정적효과병불우우단순수법복위.
Objective To analyze the efficacy of epley maneuver associated with vertigo calming for treating posterior semicircular canal benign paroxysmal positional vertigo (PC-BPPV) in young.Methods Two hundred and fifty-eight cases(age was 18-50 years old) with PC-BPPV were randomly divided into maneuver group(86 cases),betahistine group(86 cases) and vertigo calming group(86 cases).The maneuver group was treated by epley maneuver associated with placebo,2 pills per time,3 times daily for one month and follow up one month.The betahistine group and vertigo calming group were treated by epley maneuver with betahistine(12 mg/ time,Tid) or vertigo calming(2 piles/time,Tid),the same dose,period of treatment and follow-up as maneuver group.Results After one time treatment,199 cases were cured in 258 patients,including 68 cases in maneuver group,66 cases in betahistine group,65 cases in vertigo calming group,and the difference between groups was not statistically significant(x2 =0.308,P＞0.05).After treatments and followed up for one month,72 cases were cured,3 cases were effective,11 cases were invalid in maneuver group;74 cases were cured,3 cases were effective,9 cases were invalid in betahistine group;81 cases were cured,4 cases were effective,1 cases were invalid in vertigo calming group.Efficient of betahistine group,maneuver group and vertigo calming group were 89.5％,87.2％ and 98.8％,and the difference between maneuver group and betahistine group was not statistically significant(x2=58.65,P＞0.05),the difference of vertigo calming group between with other groups was statistically significant(P＜0.05).Conclusion The effects of vertigo calming in addition to Epley maneuver is significantly better than both Epley maneuver and Epley maneuver combined with betahistine in young PC-BPPV,while the effects of Epley maneuver combined with betahistine isn't better than Epley maneuver.