实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
2015年
8期
1-3,4
,共4页
心房颤动%抗凝药%华法林%达比加群酯%利伐沙班%阿哌沙班%依度沙班%贝曲西班
心房顫動%抗凝藥%華法林%達比加群酯%利伐沙班%阿哌沙班%依度沙班%貝麯西班
심방전동%항응약%화법림%체비가군지%리벌사반%아고사반%의도사반%패곡서반
Atrial fibrillation%Anticoagulants%Warfarrin%Dabigatran etexilate%Rivaroxaban%Apixaban%Edoxaban%Betrixaban
心房颤动是常见的心律失常之一，可导致卒中，且心房颤动相关卒中的危害严重。口服华法林是预防心房颤动患者发生卒中的有效措施，但华法林治疗窗窄，且易与多种食物、药物发生相互作用。新型口服抗凝药（达比加群酯、利伐沙班、阿哌沙班、依度沙班、贝曲西班）克服了华法林的一些缺点，且能更好地降低心房颤动患者卒中及出血风险，有望成为临床预防心房颤动患者卒中事件的新选择。
心房顫動是常見的心律失常之一，可導緻卒中，且心房顫動相關卒中的危害嚴重。口服華法林是預防心房顫動患者髮生卒中的有效措施，但華法林治療窗窄，且易與多種食物、藥物髮生相互作用。新型口服抗凝藥（達比加群酯、利伐沙班、阿哌沙班、依度沙班、貝麯西班）剋服瞭華法林的一些缺點，且能更好地降低心房顫動患者卒中及齣血風險，有望成為臨床預防心房顫動患者卒中事件的新選擇。
심방전동시상견적심률실상지일，가도치졸중，차심방전동상관졸중적위해엄중。구복화법림시예방심방전동환자발생졸중적유효조시，단화법림치료창착，차역여다충식물、약물발생상호작용。신형구복항응약（체비가군지、리벌사반、아고사반、의도사반、패곡서반）극복료화법림적일사결점，차능경호지강저심방전동환자졸중급출혈풍험，유망성위림상예방심방전동환자졸중사건적신선택。
Atrial fibrillation is one kind of common arrhythmia,may cause stroke,and atrial fibrillation associated stroke can lead to severe consequences. Oral warfarin is an effective measure to prevent stroke in patients with atrial fibrillation, but its therapeutic window is narrow,is easy to interact with a variety of foods and drugs. New oral anticoagulants including dabigatran etexilate,rivaroxaban,apixaban,edoxaban,betrixaban overcome many shortcomings of warfarrin,have better effect on reducing the risk of stroke and hemorrhage in patients with atrial fibrillation,is possible to become the new choice for clinical prevention of stroke in patients with atrial fibrillation.
