CAJ | 학술논문

目的：回顾性分析79例人工授精中男性 HBV 携带者的精液质量及妊娠结局，了解乙肝病毒对男性精液及妊娠结局的影响。方法：对79例男性 HBV 感染患者的女方年龄、男方年龄、不孕年限、BMI、男方精液量、液化时间、活率、前向运动精子活率、畸形率；女方妊娠率及流产率进行分析。结果：乙肝组液化时间、a 级精子比率、前向运动精子比率、精子畸形率、妊娠率及流产率与对照组比较均无统计学差异（P ＞0.05）。结论：男性乙肝携带者的精子质量无明显降低，有可能通过 HBV 对精子 DNA 的整合，对精子染色体和胚胎产生影响，从而影响妊娠结局。
목적：회고성분석79례인공수정중남성 HBV 휴대자적정액질량급임신결국，료해을간병독대남성정액급임신결국적영향。방법：대79례남성 HBV 감염환자적녀방년령、남방년령、불잉년한、BMI、남방정액량、액화시간、활솔、전향운동정자활솔、기형솔；녀방임신솔급유산솔진행분석。결과：을간조액화시간、a 급정자비솔、전향운동정자비솔、정자기형솔、임신솔급유산솔여대조조비교균무통계학차이（P ＞0.05）。결론：남성을간휴대자적정자질량무명현강저，유가능통과 HBV 대정자 DNA 적정합，대정자염색체화배태산생영향，종이영향임신결국。
Objectives:Retrospective analysis of HBV male carriers’sperm quality and outcome of preg-nancy to find if HBV could impact the sperm quality and pregnancy outcome.Methods:The female age,male age, duration of infertility,BMI,semen volume,liquefaction time,ratio of sperm activity,ratio of forward motile sperm, deformity rate,pregnancy rate,abortion rate of observation group were compared with these of control group. Results:The semen volume,liquefaction time,ratio of forward motile sperm,deformity rate,pregnancy rate and a-bortion rate in male HBV group were higher than these in control group,but the differences were not statistically sig-nificant (P >0.05).Others had no significant statistical differences (P >0.05).Conclusions:Male hepatitis B virus carriers’sperm quality was not reduced,but HBV could integrate into sperm DNA to impact sperm chromo-some and embryo quality,thus it can impact pregnancy outcome.