中国药物评价
中國藥物評價
중국약물평개
Chinese Journal of Drug Evaluation
2015年
4期
206-208
,共3页
刘大海%段曼%韩冬梅%马鹰%刘卓
劉大海%段曼%韓鼕梅%馬鷹%劉卓
류대해%단만%한동매%마응%류탁
老年宫颈癌%深静脉血栓%降纤酶%低分子肝素
老年宮頸癌%深靜脈血栓%降纖酶%低分子肝素
노년궁경암%심정맥혈전%강섬매%저분자간소
Elder cervical carcinoma%Deep vein thrombosis%Defibrase%Low molecular weight heparins
目的:探讨降纤酶与低分子肝素联合应用治疗老年女性宫颈癌术后并发深静脉血栓的临床疗效。方法:搜集我院3年内收治的老年宫颈癌术后并发深静脉血栓患者72例,随机分为两组,各36例。治疗组采用降纤酶与低分子肝素联合治疗,对照组给予单纯抗凝疗法。结果:治疗组36例患者治疗后治愈率达62.0%,显著高于对照组的32.7%,差异具有统计学意义( P<0.01)。结论:降纤酶与低分子肝素联合应用对于老年宫颈癌术后深静脉血栓形成患者具有良好的治疗效果,可提高临床治愈率,同时可有效降低远期血栓复发率及深静脉血栓后遗症。
目的:探討降纖酶與低分子肝素聯閤應用治療老年女性宮頸癌術後併髮深靜脈血栓的臨床療效。方法:搜集我院3年內收治的老年宮頸癌術後併髮深靜脈血栓患者72例,隨機分為兩組,各36例。治療組採用降纖酶與低分子肝素聯閤治療,對照組給予單純抗凝療法。結果:治療組36例患者治療後治愈率達62.0%,顯著高于對照組的32.7%,差異具有統計學意義( P<0.01)。結論:降纖酶與低分子肝素聯閤應用對于老年宮頸癌術後深靜脈血栓形成患者具有良好的治療效果,可提高臨床治愈率,同時可有效降低遠期血栓複髮率及深靜脈血栓後遺癥。
목적:탐토강섬매여저분자간소연합응용치료노년녀성궁경암술후병발심정맥혈전적림상료효。방법:수집아원3년내수치적노년궁경암술후병발심정맥혈전환자72례,수궤분위량조,각36례。치료조채용강섬매여저분자간소연합치료,대조조급여단순항응요법。결과:치료조36례환자치료후치유솔체62.0%,현저고우대조조적32.7%,차이구유통계학의의( P<0.01)。결론:강섬매여저분자간소연합응용대우노년궁경암술후심정맥혈전형성환자구유량호적치료효과,가제고림상치유솔,동시가유효강저원기혈전복발솔급심정맥혈전후유증。
Objective:The study discusses the clinical curative effects of the combined application with low molecular weight heparins (LMWHs)and defibrase.Methods:72 cases of LMWHs patients with eldly deep vein thrombosis (DVT) after operation of cervical carci-noma, they were randomly divided into 2 groups (n=36 in each group).Patients in the control group were given systemic thrombolytic therapy, meanwhile, patients in the treatment group were given defibrase and LMWHs .Results:The cure rate of treatment group (n=36) was 62.0%, which significantly higher than that of control group 32.7%, and the difference is statistically significant (P<0.01). Conclusion:After analysis of the available literature data , we can conclude that combined application with defibrase and LMWHs is sig-nificantly effective in treatment .It can increase the cure rate apparently compared with the traditional simple thrombolytic therapy .More-over, it can also effectively reduce the recurrence of DVT .