CAJ | 학술논문

目的：探讨抗生素导致患儿严重不良反应情况和临床表现。方法本次医学研究选择我院儿科2013年1月～2015年1月收治的1031名儿童患者为观察对象，其中，120例患儿抗生素治疗后出现各种不良反应症状，回顾分析患者不良反应症状的发生部位、临床表现以及药物类型。结果皮肤系统不良反应发生率较高，而免疫系统不良反应发生率则相对较低，且不同机体系统抗生素治疗后不良反应发生率对比具有统计学差异（P<0.05）。同时，大部分患者为静脉途径给药，且不良反应发生时间主要集中于首次给药后，以及给药后30 min内。结论患儿接受抗生素治疗后，常易发生皮肤、神经、消化、呼吸、循环以及免疫系统不良反应症状，因而需要对患者给药途径和类型进行适当选择。
목적：탐토항생소도치환인엄중불량반응정황화림상표현。방법본차의학연구선택아원인과2013년1월～2015년1월수치적1031명인동환자위관찰대상，기중，120례환인항생소치료후출현각충불량반응증상，회고분석환자불량반응증상적발생부위、림상표현이급약물류형。결과피부계통불량반응발생솔교고，이면역계통불량반응발생솔칙상대교저，차불동궤체계통항생소치료후불량반응발생솔대비구유통계학차이（P<0.05）。동시，대부분환자위정맥도경급약，차불량반응발생시간주요집중우수차급약후，이급급약후30 min내。결론환인접수항생소치료후，상역발생피부、신경、소화、호흡、순배이급면역계통불량반응증상，인이수요대환자급약도경화류형진행괄당선택。
Objective To investigate the cause of antibiotics in children with serious adverse reactions and clinical manifestations. Methods The medical research to select between treated from January 2013 to January 2015 in our hospital pediatric patients 1 031 children observed object,wherein a variety of adverse symptoms after 120 cases of children with antibiotic treatment,retrospective analysis of patients with poor site reactions occur symptoms,clinical manifestations and drug types. Results Skin higher incidence of adverse reactions,and immune system incidence of adverse reactions were relatively low,and the different body systems after antibiotic treatment incidence of adverse reactions contrast had statistical y significant difference(P<0.05).At the same time,most patients intravenous routes of administration,and the incidence of adverse reactions after the first time focused on the administration, as wel as within 30 min after dosing. Conclusion The patients received antibiotic treatment,often prone skin,nervous,digestive,respiratory symptoms of adverse reactions,circulation and immune system,and thus the need for the patient and the type of route of administration is appropriately selected.