中国伤残医学
中國傷殘醫學
중국상잔의학
Chinese Journal of Trauma and Disability Medicine
2015年
20期
33-35
,共3页
李利明%白莉%程志云%王皓
李利明%白莉%程誌雲%王皓
리리명%백리%정지운%왕호
慢性荨麻疹%IL-4%户尘螨sIgE
慢性蕁痳疹%IL-4%戶塵螨sIgE
만성담마진%IL-4%호진만sIgE
Chronic urticaria%Interleukin-4%Immunoglobulin E of Dermatophagoides pteronyssinus
目的：研究及探讨户尘螨特异性IgE与IL－4水平在慢性荨麻疹病人血清中的表达及相关性。方法：选择对户尘螨过敏的慢性荨麻疹患者41例，健康对照组20例；采用免疫印迹法测定慢性荨麻疹患者血清中户尘螨特异性IgE指标，采用ELISA法测定慢性荨麻疹患者血清中IL－4的指标。结果：慢性荨麻疹病人血清中户尘螨sIgE水平明显高于健康对照组，IL－4指标亦明显高于健康对照组，组间差异有统计学意义（ P＜0．05）；慢性荨麻疹患者血清中户尘螨sIgE与IL－4水平无显著相关性（r为0．171，P＞0．05）。结论：户尘螨特异性IgE、IL－4水平与CU的发病有关；慢性荨麻疹病人血清中IgE水平的影响因素众多。
目的：研究及探討戶塵螨特異性IgE與IL－4水平在慢性蕁痳疹病人血清中的錶達及相關性。方法：選擇對戶塵螨過敏的慢性蕁痳疹患者41例，健康對照組20例；採用免疫印跡法測定慢性蕁痳疹患者血清中戶塵螨特異性IgE指標，採用ELISA法測定慢性蕁痳疹患者血清中IL－4的指標。結果：慢性蕁痳疹病人血清中戶塵螨sIgE水平明顯高于健康對照組，IL－4指標亦明顯高于健康對照組，組間差異有統計學意義（ P＜0．05）；慢性蕁痳疹患者血清中戶塵螨sIgE與IL－4水平無顯著相關性（r為0．171，P＞0．05）。結論：戶塵螨特異性IgE、IL－4水平與CU的髮病有關；慢性蕁痳疹病人血清中IgE水平的影響因素衆多。
목적：연구급탐토호진만특이성IgE여IL－4수평재만성담마진병인혈청중적표체급상관성。방법：선택대호진만과민적만성담마진환자41례，건강대조조20례；채용면역인적법측정만성담마진환자혈청중호진만특이성IgE지표，채용ELISA법측정만성담마진환자혈청중IL－4적지표。결과：만성담마진병인혈청중호진만sIgE수평명현고우건강대조조，IL－4지표역명현고우건강대조조，조간차이유통계학의의（ P＜0．05）；만성담마진환자혈청중호진만sIgE여IL－4수평무현저상관성（r위0．171，P＞0．05）。결론：호진만특이성IgE、IL－4수평여CU적발병유관；만성담마진병인혈청중IgE수평적영향인소음다。
Objective:To explore the correlation between the specific Immunoglobulin E(sIgE) of Dermatophagoides pteronyssinus ( Derp) and Interleukin-4( IL-4) levels presented in patients with chronic urticaria( CU) .Methods:The serum levels of sIgE and IL-4 were determined by immunoblotting and ELISA respectively in 41 patients who are allergic to Der p and 20 normal controls.Results:The levels of sIgE and IL-4 were significant higher than those in normal controls(P<0.05).SIgE of Der p had no positive correlation with IL-4(r=0.717,P>0.05).Conclusion:This essay proves that sIgE of Der p and IL-4 play important roles in the process of CU.
