CAJ | 학술논문

目的：探讨超声造影与增强 MRI 两种方法在眼眶良恶性肿瘤鉴别诊断中的应用价值。方法选取74例眼眶占位患者(74只眼),以病理诊断为金标准分为良性组和恶性组。行超声造影检查,所得图像资料导入 SonoLiver 软件进行分析。比较超声造影、增强 MRI 及联合诊断(超声造影+增强MRI)3种方法的诊断符合率及增强强度差异,分析超声造影定量参数指标。结果(1)良性组中上述3种方法的诊断符合率分别为90.0%、80.0%、96.0%,两两比较仅增强 MRI 与联合诊断两者间差异有统计学意义(P <0.05)；恶性组中上述3种方法的诊断符合率分别为75.0%、79.2%、95.8%,两两比较差异均无统计学意义(P >0.05)。(2)超声造影的增强强度在良恶性组中分布存在不同(P <0.05)；增强 MRI 的增强强度在良恶性组中分布无明显差异(P >0.05)。(3)超声造影时间-强度曲线(TIC)获取的参数中：上升时间(RT)、达峰时间(TTP)、半洗脱时间在良恶性组间差异有统计学意义(P <0.05)；而造影剂到达时间(AT)、平均渡越时间(mTT)在两组间差异无统计学意义(P >0.05)。结论超声造影对眼眶良性肿瘤的诊断符合率高于增强 MRI,超声造影增强强度及时间-强度曲线对鉴别眼眶良恶性肿瘤有着一定的帮助。
목적：탐토초성조영여증강 MRI 량충방법재안광량악성종류감별진단중적응용개치。방법선취74례안광점위환자(74지안),이병리진단위금표준분위량성조화악성조。행초성조영검사,소득도상자료도입 SonoLiver 연건진행분석。비교초성조영、증강 MRI 급연합진단(초성조영+증강MRI)3충방법적진단부합솔급증강강도차이,분석초성조영정량삼수지표。결과(1)량성조중상술3충방법적진단부합솔분별위90.0%、80.0%、96.0%,량량비교부증강 MRI 여연합진단량자간차이유통계학의의(P <0.05)；악성조중상술3충방법적진단부합솔분별위75.0%、79.2%、95.8%,량량비교차이균무통계학의의(P >0.05)。(2)초성조영적증강강도재량악성조중분포존재불동(P <0.05)；증강 MRI 적증강강도재량악성조중분포무명현차이(P >0.05)。(3)초성조영시간-강도곡선(TIC)획취적삼수중：상승시간(RT)、체봉시간(TTP)、반세탈시간재량악성조간차이유통계학의의(P <0.05)；이조영제도체시간(AT)、평균도월시간(mTT)재량조간차이무통계학의의(P >0.05)。결론초성조영대안광량성종류적진단부합솔고우증강 MRI,초성조영증강강도급시간-강도곡선대감별안광량악성종류유착일정적방조。
Objective To evaluate the ability of contrast-enhanced ultrasonography (CEUS ) compared to enhanced MRI scan in differential diagnosis of benign and malign tumor of orbit.Methods CEUS and enhanced MRI was performed in 74 patients with tumor of orbit.These patients were divided into two groups:benign and malignant tumor depended on histological diagnosis.The results were analysed with SonoLiver software.The coincidence rate of diagnosis and enhancement intensity among CEUS,MRI and CEUS+ MRI were compared and the quantitative parameters of CEUS were analysed.Results (1 )The diagnostic accordance rate of benign group by three methods were 90.0%,80.0% and 96.0% respectively, there was statistical difference for diagnostic coincidence rate between the MRI and CEUS+ MRI(P <0.05).The diagnostic accordance rate of malignant group by the above three methods were 75.0%,79.2%and 95.8% respectively,there was no statistical difference for diagnostic coincidence rate between the three methods(all P > 0.05 ).(2 )The enhancement intensity of CEUS was different between benign and malignant groups (P <0.05).There was no statistical difference between benign and malignant groups by MRI method (P >0.05).(3)The parameters of tumor imaging obtained time intensity curve(TIC):rise time (RT),half elution time and time to peaking (TTP)were significantly different between benign and malignant groups(P <0.05).While there was no significant difference of parameters as mean transit time (mTT)and arrived time (AT)(P >0.05).Conclusions CEUS had higher diagnostic accuracy than MRI in benign orbital tumor.The contrast enhancement intensity and time-intensity curves provide valuable diagnostic information for differential diagnosis of benign and malignant orbital tumor.