CAJ | 학술논문

目的：分析美金刚治疗血管性痴呆精神行为症状临床疗效。方法选取从2013年8月～2015年8月收治的40例血管性痴呆伴精神行为症状，使用美金刚治疗，对比入组患者治疗前、治疗后的临床疗效。结果入组患者治疗12周后，ADL、BEHAVE-AD、MMSE评分优于治疗前（P<0.05）。药物不良反应发生率为10.00%。结论对血管性痴呆伴精神行为症状患者采用美金刚治疗，可改善患者日常生活能力、精神行为症状及认知功能，安全有效。
목적：분석미금강치료혈관성치태정신행위증상림상료효。방법선취종2013년8월～2015년8월수치적40례혈관성치태반정신행위증상，사용미금강치료，대비입조환자치료전、치료후적림상료효。결과입조환자치료12주후，ADL、BEHAVE-AD、MMSE평분우우치료전（P<0.05）。약물불량반응발생솔위10.00%。결론대혈관성치태반정신행위증상환자채용미금강치료，가개선환자일상생활능력、정신행위증상급인지공능，안전유효。
Objective To analyze the clinical efficacy of memantine in treatment of vascular dementia behavioral and psychiatric symptoms. Methods From August 2013 to August 2015,40 cases of vascular dementia had behavioral and psychological symptoms,treatment with memantine and contrast into groups of patients before treatment,after treatment of clinical efficacy. Results After 12 weeks of treatment,the scores of ADL,BEHAVE-AD and MMSE were significantly better than before treatment(P<0.05). The incidence of adverse drug reactions was 10%. Conclusion On vascular dementia with behavioral and psychiatric symptoms in patients treated with memantine,improve patients activities of daily living(ADL),neuropsychiatric symptoms and cognitive function,safe and effective.