实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
2015年
8期
83-85
,共3页
卒中%依达拉奉%奥扎格雷%克栓酶%治疗结果
卒中%依達拉奉%奧扎格雷%剋栓酶%治療結果
졸중%의체랍봉%오찰격뢰%극전매%치료결과
Stroke%Edaravone%Ozagrel%Defibrin%Treatment outcome
目的：观察依达拉奉、奥扎格雷联合克栓酶治疗急性脑卒中的临床疗效。方法选择2014年1月—2015年2月湖北医药学院附属太和医院收治的急性脑卒中患者60例，按照入院先后顺序将患者分为对照组和观察组，各30例。对照组患者采用依达拉奉和奥扎格雷进行治疗，观察组患者采用依达拉奉、奥扎格雷联合克栓酶进行治疗，两组患者均治疗2周。比较两组患者治疗前后神经功能缺损程度评分、美国国立卫生研究院卒中量表（ NIHSS）评分、日常生活活动能力量表（ ADL）评分及临床疗效。结果治疗前两组患者神经功能缺损程度评分、NIHSS评分及ADL评分比较，差异无统计学意义（ P>0.05）；治疗后观察组患者神经功能缺损程度评分、NIHSS评分低于对照组，ADL评分高于对照组（P<0.05）。观察组患者临床疗效优于对照组（u=2.530，P=0.011）。结论依达拉奉、奥扎格雷联合克栓酶治疗急性脑卒中的临床疗效确切，能有效改善患者神经功能缺损程度、提高患者日常生活能力。
目的：觀察依達拉奉、奧扎格雷聯閤剋栓酶治療急性腦卒中的臨床療效。方法選擇2014年1月—2015年2月湖北醫藥學院附屬太和醫院收治的急性腦卒中患者60例，按照入院先後順序將患者分為對照組和觀察組，各30例。對照組患者採用依達拉奉和奧扎格雷進行治療，觀察組患者採用依達拉奉、奧扎格雷聯閤剋栓酶進行治療，兩組患者均治療2週。比較兩組患者治療前後神經功能缺損程度評分、美國國立衛生研究院卒中量錶（ NIHSS）評分、日常生活活動能力量錶（ ADL）評分及臨床療效。結果治療前兩組患者神經功能缺損程度評分、NIHSS評分及ADL評分比較，差異無統計學意義（ P>0.05）；治療後觀察組患者神經功能缺損程度評分、NIHSS評分低于對照組，ADL評分高于對照組（P<0.05）。觀察組患者臨床療效優于對照組（u=2.530，P=0.011）。結論依達拉奉、奧扎格雷聯閤剋栓酶治療急性腦卒中的臨床療效確切，能有效改善患者神經功能缺損程度、提高患者日常生活能力。
목적：관찰의체랍봉、오찰격뢰연합극전매치료급성뇌졸중적림상료효。방법선택2014년1월—2015년2월호북의약학원부속태화의원수치적급성뇌졸중환자60례，안조입원선후순서장환자분위대조조화관찰조，각30례。대조조환자채용의체랍봉화오찰격뢰진행치료，관찰조환자채용의체랍봉、오찰격뢰연합극전매진행치료，량조환자균치료2주。비교량조환자치료전후신경공능결손정도평분、미국국립위생연구원졸중량표（ NIHSS）평분、일상생활활동능역량표（ ADL）평분급림상료효。결과치료전량조환자신경공능결손정도평분、NIHSS평분급ADL평분비교，차이무통계학의의（ P>0.05）；치료후관찰조환자신경공능결손정도평분、NIHSS평분저우대조조，ADL평분고우대조조（P<0.05）。관찰조환자림상료효우우대조조（u=2.530，P=0.011）。결론의체랍봉、오찰격뢰연합극전매치료급성뇌졸중적림상료효학절，능유효개선환자신경공능결손정도、제고환자일상생활능력。
Objective To observe the clinical effect of edaravone and ozagrel combined with defibrin on acute stroke. Methods From January 2014 to February 2015,a total of 60 patients with acute stroke were selected in Taihe Hospital Affiliated to Hubei Medicine College, and they were divided into control group and observation group according to the order of hospitalization,each of 30 cases. Patients of control group were given edaravone and ozagrel,while patients of observation group were given edaravone and ozagrel combined with defibrin,both groups treated for 2 weeks. Neurological deficit score,NIHSS score and ADL score before and after treatment and clinical effect were compared between the two groups. Results No statistically significant differences of neurological deficit score,NIHSS score or ADL score was found between the two groups before treatment(P>0. 05);after treatment,neurological deficit score and NIHSS score of observation group were statistically significantly lower than those of control group,while ADL score of observation group was statistically significantly higher than that of control group ( P <0. 05 ). The clinical effect of observation group was statistically significantly better than that of control group(u=2. 530,P=0. 011). Conclusion Edaravone and ozagrel combined with defibrin has certain clinical effect on acute stroke,which can effectively reduce the degree of nervous functional defects,improve the activity of daily living.
