CAJ | 학술논문

目的：探究在胃食管反流的临床治疗中埃索美拉唑治疗的应用效果。方法整群选取2012年8月-2014年12月在该院消化科治疗的胃食管反流患者98例，按照随机分组原则将其分为对照组和治疗组，对照组患者采取常规的对症治疗，治疗组患者则在常规对症治疗的同时采用埃索美拉唑进行口服治疗，对比两组患者的临床治疗效果，其临床治疗检测指标主要包括患者的烧心、泛酸以及胃食管反流导致的炎症病症以及相应的炎症愈合情况。结果两组患者在治疗过程中均未见严重的不良反应相关病症，治疗组患者的临床治疗有效率(91.8%)明显高于对照组(53.1%)，差异有统计学意义(P<0.05)。结论在胃食管反流病症的临床治疗中结合埃索美拉唑进行治疗能够显著改善患者的临床病症，并且具有安全、高效的特性，值得在临床上推广应用。
목적：탐구재위식관반류적림상치료중애색미랍서치료적응용효과。방법정군선취2012년8월-2014년12월재해원소화과치료적위식관반류환자98례，안조수궤분조원칙장기분위대조조화치료조，대조조환자채취상규적대증치료，치료조환자칙재상규대증치료적동시채용애색미랍서진행구복치료，대비량조환자적림상치료효과，기림상치료검측지표주요포괄환자적소심、범산이급위식관반류도치적염증병증이급상응적염증유합정황。결과량조환자재치료과정중균미견엄중적불량반응상관병증，치료조환자적림상치료유효솔(91.8%)명현고우대조조(53.1%)，차이유통계학의의(P<0.05)。결론재위식관반류병증적림상치료중결합애색미랍서진행치료능구현저개선환자적림상병증，병차구유안전、고효적특성，치득재림상상추엄응용。
Objective To explore the application effect of esomeprazole for clinical treatment in gastroesophageal reflux in. Meth-ods a total of August 2012 to December 2014 in the Department of digestive diseases in our hospital treatment of gastro esophageal anti flow 98 patients, in accordance with the principle of randomization will be divided into control group and treatment group, control group patients were treated with conventional symptomatic treatment, treatment group in the conventional symp-tomatic treatment and oral treatment with esomeprazole, compared two groups of patients with clinical curative effect, the clinical indexes including patients with heartburn, pantothenic acid and esophageal and gastric anti flow leads to inflammatory disorders and corresponding inflammatory healing. Results Two groups of patients were not seen in the process of treatment of severe ad-verse reactions related to disease, the treatment group patients with the clinical treatment of efficient (91.8%) is significantly higher than the control group (53.1%), significant difference has statistical significance (P<0.05). Conclusion in the clinical treatment of gastroesophageal reflux disease combined with esomeprazole treatment can significantly improve the patient's clinical symptoms, and has the advantages of safety, efficient characteristics, is worthy to be popularized in clinic.