CAJ | 학술논문

目的：探讨不同甲状腺激素水平及131I剂量对甲状腺癌患者一次清甲成功率的影响研究,为进一步提高临床治疗效果提供新的资料和思路。方法回顾性分析该院于2011年1月-2014年12月收治的甲状腺癌患者69例,所有患者均在外科手术治疗后再行碘治疗,根据不同甲状腺激素水平及131I剂量对患者进行分组,分析不同分组间的一次清甲成功率。结果促甲状腺激素水平高于30③IU/mL和131I剂量高于3.7 GBq的甲状腺癌患者一次清甲成功率明显高(P<0.05),其中年龄、性别、碘摄取量病理分型等对一次清甲成功与否差异无统计学意义(P>0.05)。结论对于甲状腺癌术后患者,碘具有治疗难度低、副作用小、有效率较高等特点,可以在临床上推广使用。对于促甲状腺激素水平高于30③IU/mL临床效果更佳,131I剂量高于3.7 GBq临床效果满意。
목적：탐토불동갑상선격소수평급131I제량대갑상선암환자일차청갑성공솔적영향연구,위진일보제고림상치료효과제공신적자료화사로。방법회고성분석해원우2011년1월-2014년12월수치적갑상선암환자69례,소유환자균재외과수술치료후재행전치료,근거불동갑상선격소수평급131I제량대환자진행분조,분석불동분조간적일차청갑성공솔。결과촉갑상선격소수평고우30③IU/mL화131I제량고우3.7 GBq적갑상선암환자일차청갑성공솔명현고(P<0.05),기중년령、성별、전섭취량병리분형등대일차청갑성공여부차이무통계학의의(P>0.05)。결론대우갑상선암술후환자,전구유치료난도저、부작용소、유효솔교고등특점,가이재림상상추엄사용。대우촉갑상선격소수평고우30③IU/mL림상효과경가,131I제량고우3.7 GBq림상효과만의。
Objective To investigate the different levels of thyroid hormone and 131I dose on the success rate of a time Remove all thyroid cancer in patients, provide new data and ideas in order to improve further clinical effect and cut down poison and side ef-fect. Methods 69 patients with thyroid cancer who were treated in the hospital from December 2014 to January 2011 were retro-spectively analyzed. All patients were treated with I after surgical treatment. The patients were divided into different groups accord-ing to different thyroid hormone levels and 131I dose. Results The TSH level higher than 30 IU/mL and 131I doses higher than 3.7 GBq thyroid cancer patients once a clear success rate were significantly higher (P<0.05), including age, gender, pathological type and iodine uptake on the time of a success was not significantly affected (P>0.05). Conclusion For the patients after thyroid carci-noma surgery, I had the characteristic that easy to treat, fewer side effect, higher efficiency, which is worthy of clinical populariza-tion. The clinical effect of thyroid stimulating hormone levels higher than 30 IU/mL is better, the clinical effect of 3.7 GBq higher than 131I doses is satisfactory.