中国基层医药
中國基層醫藥
중국기층의약
Chinese Journal of Primary Medicine and Pharmacy
2015年
19期
2967-2969
,共3页
流产,稽流%清宫术%戊酸雌二醇%屈螺酮
流產,稽流%清宮術%戊痠雌二醇%屈螺酮
유산,계류%청궁술%무산자이순%굴라동
Abortion,missed%Curettage%Estradiol valerate%Drospirenone
目的：观察戊酸雌二醇和屈螺酮在稽留流产清宫术前后应用的临床疗效。方法选择稽留流产并行清宫术的患者160例，采用数字表法随机分为观察组和对照组，两组患者在清宫术前1 h 均口服米索前列醇400μg，后充盈膀胱，在 B 超引导下行清宫术，术后常规用抗生素3 d。观察组清宫术前3 d 予戊酸雌二醇4 mg 口服，每天2次，连服3 d；清宫术后当天起予屈螺酮口服，每晚1片，连用3个周期。对照组清宫术前后不予戊酸雌二醇和屈螺酮。观察两组手术时间、术中出血量、术后阴道流血时间及流血量、首次月经复潮时间、子宫内膜修复及术后并发症发生情况。结果对照组手术时间、术中出血量、首次月经复潮时间、子宫内膜厚度、术后并发症发生率分别为（6．05±0．49）min、（50．88±9．18）mL、（36．51±1．95）d、（4．08±0．56）mm、15．0％，观察组分别为（4．46±0．45）min、（35．63±8．24）mL、（29．28±1．57）d、（6．11±0．76）mm、3．8％，两组手术时间、术中出血量﹑首次月经复潮时间、子宫内膜厚度、术后并发症发生率差异均有统计学意义（t ＝－11．264、－16．643、－24．93、19．151，χ2＝5．959，均 P ＜0．05）。结论稽留流产清宫术前后给予戊酸雌二醇和屈螺酮，能有效改善清宫术的近远期并发症，提高清宫术的临床疗效。
目的：觀察戊痠雌二醇和屈螺酮在稽留流產清宮術前後應用的臨床療效。方法選擇稽留流產併行清宮術的患者160例，採用數字錶法隨機分為觀察組和對照組，兩組患者在清宮術前1 h 均口服米索前列醇400μg，後充盈膀胱，在 B 超引導下行清宮術，術後常規用抗生素3 d。觀察組清宮術前3 d 予戊痠雌二醇4 mg 口服，每天2次，連服3 d；清宮術後噹天起予屈螺酮口服，每晚1片，連用3箇週期。對照組清宮術前後不予戊痠雌二醇和屈螺酮。觀察兩組手術時間、術中齣血量、術後陰道流血時間及流血量、首次月經複潮時間、子宮內膜脩複及術後併髮癥髮生情況。結果對照組手術時間、術中齣血量、首次月經複潮時間、子宮內膜厚度、術後併髮癥髮生率分彆為（6．05±0．49）min、（50．88±9．18）mL、（36．51±1．95）d、（4．08±0．56）mm、15．0％，觀察組分彆為（4．46±0．45）min、（35．63±8．24）mL、（29．28±1．57）d、（6．11±0．76）mm、3．8％，兩組手術時間、術中齣血量﹑首次月經複潮時間、子宮內膜厚度、術後併髮癥髮生率差異均有統計學意義（t ＝－11．264、－16．643、－24．93、19．151，χ2＝5．959，均 P ＜0．05）。結論稽留流產清宮術前後給予戊痠雌二醇和屈螺酮，能有效改善清宮術的近遠期併髮癥，提高清宮術的臨床療效。
목적：관찰무산자이순화굴라동재계류유산청궁술전후응용적림상료효。방법선택계류유산병행청궁술적환자160례，채용수자표법수궤분위관찰조화대조조，량조환자재청궁술전1 h 균구복미색전렬순400μg，후충영방광，재 B 초인도하행청궁술，술후상규용항생소3 d。관찰조청궁술전3 d 여무산자이순4 mg 구복，매천2차，련복3 d；청궁술후당천기여굴라동구복，매만1편，련용3개주기。대조조청궁술전후불여무산자이순화굴라동。관찰량조수술시간、술중출혈량、술후음도류혈시간급류혈량、수차월경복조시간、자궁내막수복급술후병발증발생정황。결과대조조수술시간、술중출혈량、수차월경복조시간、자궁내막후도、술후병발증발생솔분별위（6．05±0．49）min、（50．88±9．18）mL、（36．51±1．95）d、（4．08±0．56）mm、15．0％，관찰조분별위（4．46±0．45）min、（35．63±8．24）mL、（29．28±1．57）d、（6．11±0．76）mm、3．8％，량조수술시간、술중출혈량﹑수차월경복조시간、자궁내막후도、술후병발증발생솔차이균유통계학의의（t ＝－11．264、－16．643、－24．93、19．151，χ2＝5．959，균 P ＜0．05）。결론계류유산청궁술전후급여무산자이순화굴라동，능유효개선청궁술적근원기병발증，제고청궁술적림상료효。
Objective To observe the clinical effects of estradiol valerate and drospirenone applying in missed abortion and curettage before and after operation.Methods 160 patients with missed abortion parallel curet-tage were chosen,who were randomly divided into the observation group and control group by the number table meth-od.Two groups of patients were oral misoprostol 400 g before uterine curettage 1 h,and then were treated with ultra-sonic curettage after filling the bladder and postoperative routine use of antibiotics for 3 D.3 D before the curettage, observation group were treated with oral estradiol valerate 4 mg for 3 D,2times a day..After curettage of the day, drospirenone orally was given for 1 tablet every night,used in conjunction a cycle for 3weeks.The control group before and after curettage were given without estradiol valerate and drospirenone.Operation time,bleeding volume,postopera-tive bleeding time and bleeding volume,the time of the first menstrual cycle,endometrial repair and postoperative complications were observed in the two groups.Results In the control group,operation time,intraoperative bleeding volume,for the first time the resumption of menstruation tide time,endometrial thickness,postoperative complication rate were (6.05 ±0.49)min,(50.88 ±9.18)mL,(36.51 ±1.95)d,(4.08 ±0.56)mm and 15.0%;the data of the observation group were (4.46 ±0.45)min,(35.63 ±8.24)mL,of (29.28 ±1.57)d,(6.11 ±0.76)mm and 3.8%.The operation time,intraoperative bleeding volume,for the first time the resumption of menstruation tide time, endometrial thickness,postoperative complication rate differences of the two groups were statistically significant(t =-11.264,-16.643,-24.93,19.151,χ2 =5.959,all P <0.05).Conclusion Giving estradiol valerate and flexor buspirone before and after missed abortion and curettage,can effectively improve the short -term and long -term complications of uterine curettage,and improve the clinical efficacy of dilatation and curettage.
