CAJ | 학술논문

目的：观察林蛙油对大鼠酒精性肝纤维化的作用。方法采用酒精灌胃的方法复制大鼠酒精性肝纤维化模型，将模型组给予林蛙油和秋水仙碱治疗，取大鼠肝组织进行检测，透射电镜观察大鼠肝脏病理学改变。结果透射电镜结果显示，林蛙油治疗后，大多肝纤维化组织向正常组织转化。结论林蛙油通过抑制肝星状细胞的活化逆转大鼠酒精性肝纤维化。
목적：관찰림와유대대서주정성간섬유화적작용。방법채용주정관위적방법복제대서주정성간섬유화모형，장모형조급여림와유화추수선감치료，취대서간조직진행검측，투사전경관찰대서간장병이학개변。결과투사전경결과현시，림와유치료후，대다간섬유화조직향정상조직전화。결론림와유통과억제간성상세포적활화역전대서주정성간섬유화。
Objective To observe the effect of oviductus ranae on alcoholic liver fibrosis in rats. Methods The alcohol irrigation stomach method wine replication model of alcoholic liver fibrosis in rats,model group received the oviductus ranae and colchicine treatment,rat liver tissue were detected,pathological changes of rat liver were observed by transmission electron microscope. Results Transmission electron microscopy showed that most of the liver fibrosis tissues were transformed to normal tissues. Conclusion By inhibiting the activation of hepatic stel ate cel s and reverse the alcoholic liver fibrosis in rats.