中国性科学
中國性科學
중국성과학
Chinese Journal of Human Sexuality
2015年
9期
25-28
,共4页
何华%余小蓉%张正琼%朱晓兰
何華%餘小蓉%張正瓊%硃曉蘭
하화%여소용%장정경%주효란
围绝经期%功能失调性子宫出血%宫血宁胶囊%米非司酮%性激素
圍絕經期%功能失調性子宮齣血%宮血寧膠囊%米非司酮%性激素
위절경기%공능실조성자궁출혈%궁혈저효낭%미비사동%성격소
Perimenopausal period%Dysfunctional uterine bleeding%Gongxuening capsule%Mife-pristone%Sex hormone
目的：探讨宫血宁胶囊联合米非司酮对围绝经期功能失调性子宫出血患者血清性激素的影响。方法：92例围绝经期功能失调性子宫出血患者，随机分为两组，各46例。对照组给予炔诺酮治疗，观察组给予宫血宁胶囊联合米非司酮治疗。结果：观察组总有效率为95.65％高于对照组总有效率76.09％，差异具有统计学意义（P ＜0.01）。观察组复发率为2.17％少于对照组的复发率17.39％，差异具有统计学意义（P ＜0.05）。治疗后，观察组患者的 FSH（22.05±5.31）U ／L、LH（21.46±3.35）U ／L、E2（118.27±30.42） pmol／L 都低于对照组患者 FSH（54.84±7.89）U ／L、LH（38.53±6.68）U ／L 、E2（332.48±72.94）pmol／L，差异具有统计学意义（P ＜0.01）。治疗后，观察组患者 HGB 水平（107.54±10.21）g／L 高于对照组患者 HGB水平（96.42±10.46）g／L，差异具有统计学意义（P ＜0.01）。治疗后，观察组患者子宫内膜厚度（4.26±0.84）mm 低于对照组患者子宫内膜厚度（5.52±1.13）mm，差异具有统计学意义（P ＜0.01）。观察组患者控制出血时间（21.63±6.89）h、完全止血时间（56.92±14.17）h 都少于对照组患者控制出血时间（32.18±7.72）h、完全止血时间（67.48±23.67）h，差异具有统计学意义（P ＜0.05）。结论：宫血宁胶囊联合米非司酮治疗围绝经期功能失调性子宫出血疗效显著，能改善患者血清性激素水平，及时有效控制出血，改善子宫内膜厚度。
目的：探討宮血寧膠囊聯閤米非司酮對圍絕經期功能失調性子宮齣血患者血清性激素的影響。方法：92例圍絕經期功能失調性子宮齣血患者，隨機分為兩組，各46例。對照組給予炔諾酮治療，觀察組給予宮血寧膠囊聯閤米非司酮治療。結果：觀察組總有效率為95.65％高于對照組總有效率76.09％，差異具有統計學意義（P ＜0.01）。觀察組複髮率為2.17％少于對照組的複髮率17.39％，差異具有統計學意義（P ＜0.05）。治療後，觀察組患者的 FSH（22.05±5.31）U ／L、LH（21.46±3.35）U ／L、E2（118.27±30.42） pmol／L 都低于對照組患者 FSH（54.84±7.89）U ／L、LH（38.53±6.68）U ／L 、E2（332.48±72.94）pmol／L，差異具有統計學意義（P ＜0.01）。治療後，觀察組患者 HGB 水平（107.54±10.21）g／L 高于對照組患者 HGB水平（96.42±10.46）g／L，差異具有統計學意義（P ＜0.01）。治療後，觀察組患者子宮內膜厚度（4.26±0.84）mm 低于對照組患者子宮內膜厚度（5.52±1.13）mm，差異具有統計學意義（P ＜0.01）。觀察組患者控製齣血時間（21.63±6.89）h、完全止血時間（56.92±14.17）h 都少于對照組患者控製齣血時間（32.18±7.72）h、完全止血時間（67.48±23.67）h，差異具有統計學意義（P ＜0.05）。結論：宮血寧膠囊聯閤米非司酮治療圍絕經期功能失調性子宮齣血療效顯著，能改善患者血清性激素水平，及時有效控製齣血，改善子宮內膜厚度。
목적：탐토궁혈저효낭연합미비사동대위절경기공능실조성자궁출혈환자혈청성격소적영향。방법：92례위절경기공능실조성자궁출혈환자，수궤분위량조，각46례。대조조급여결낙동치료，관찰조급여궁혈저효낭연합미비사동치료。결과：관찰조총유효솔위95.65％고우대조조총유효솔76.09％，차이구유통계학의의（P ＜0.01）。관찰조복발솔위2.17％소우대조조적복발솔17.39％，차이구유통계학의의（P ＜0.05）。치료후，관찰조환자적 FSH（22.05±5.31）U ／L、LH（21.46±3.35）U ／L、E2（118.27±30.42） pmol／L 도저우대조조환자 FSH（54.84±7.89）U ／L、LH（38.53±6.68）U ／L 、E2（332.48±72.94）pmol／L，차이구유통계학의의（P ＜0.01）。치료후，관찰조환자 HGB 수평（107.54±10.21）g／L 고우대조조환자 HGB수평（96.42±10.46）g／L，차이구유통계학의의（P ＜0.01）。치료후，관찰조환자자궁내막후도（4.26±0.84）mm 저우대조조환자자궁내막후도（5.52±1.13）mm，차이구유통계학의의（P ＜0.01）。관찰조환자공제출혈시간（21.63±6.89）h、완전지혈시간（56.92±14.17）h 도소우대조조환자공제출혈시간（32.18±7.72）h、완전지혈시간（67.48±23.67）h，차이구유통계학의의（P ＜0.05）。결론：궁혈저효낭연합미비사동치료위절경기공능실조성자궁출혈료효현저，능개선환자혈청성격소수평，급시유효공제출혈，개선자궁내막후도。
Objectives:To investigate the effect of Gongxuening capsule combined with mifepristone inter-vention on the serum sex hormone levels of patients with perimenopausal dysfunctional uterine bleeding.Methods:92 patients with perimenopausal dysfunctional uterine bleeding,were randomly divided into two groups,46 cases in each.Control group was given norethisterone treatment while observation group was given Gongxuening capsule com-bined with mifepristone.Results:The total efficiency of the observation group was 95.65%,higher than that of the control group of 76.09%,with statistically significant differences (P <0.01).The recurrence rate was 2.17% in the observation group,smaller than that in the control group of 17.39%,with statistically significant difference (P <0.05).After treatment,FSH (22.05 ±5.31)U /L,LH (21.46 ±3.35)U /L,E2 (118.27 ±30.42)pmol/L in the observation group were lower than those in the control group which were FSH (54.84 ±7.89)U /L,LH (38.53 ±6.68)U /L,E2 (332.48 ±72.94)pmol/L respectively,with statistically significant difference (P <0.01).After treatment,the level of HGB (107.54 ±10.21)g/L in the observation group was higher than that in the control group of (96.42 ±10.46)g/L,with statistically significant difference (P <0.01).After treatment,the thickness of endometrium (4.26 ±0.84)mm in the observation group was lower than that in the control group of (5.52 ±1.13)mm,with statistically significant difference (P <0.01).The bleeding control time (21.63 ±6.89) h and hemostasis time (56.92 ±14.17)h in the observation group were less than those in the control group which were (32.18 ±7.72)h and (67.48 ±23.67)h respectively,with statistically significant difference (P <0.05). Conclusions:Gongxuening capsule combined with mifepristone is of good curative effect in the treatment of perim-enopausal dysfunctional uterine bleeding,which can improve the serum sex hormone levels of patients timely,re-duce bleeding of patients and improve the endometrial thickness.
