CAJ | 학술논문

采用色谱技术对 Fusarium solani 387＃的次级代谢产物进行分离纯化，根据化合物的理化性质、波谱数据以及与文献谱图、数据对照的方法确定化合物的结构。从南海红树林内生真菌 Fusarium solani 387＃的次级代谢产物中分离得到了9个镰红菌素类化合物，分别鉴定为5（R）-deoxyfusarubin （1）、5（S）-deoxyfusarubin （2）、3-methyl ether fusarubin （3）、Fusarubin （4）、Anhydrofusarabin （5）、Anhydro-5-deoxyfusarubin （6）、2-acetonyl-3-methyl-7-methoxy-naphthazarin （7）、Javanicin （8）、2-acetonyl-3-methyl-5-hydrogen-7-methoxy-naphthazarin （9）。通过 X －射线单晶衍射首次确定了化合物1和2的绝对构型及存在形式。
채용색보기술대 Fusarium solani 387＃적차급대사산물진행분리순화，근거화합물적이화성질、파보수거이급여문헌보도、수거대조적방법학정화합물적결구。종남해홍수림내생진균 Fusarium solani 387＃적차급대사산물중분리득도료9개렴홍균소류화합물，분별감정위5（R）-deoxyfusarubin （1）、5（S）-deoxyfusarubin （2）、3-methyl ether fusarubin （3）、Fusarubin （4）、Anhydrofusarabin （5）、Anhydro-5-deoxyfusarubin （6）、2-acetonyl-3-methyl-7-methoxy-naphthazarin （7）、Javanicin （8）、2-acetonyl-3-methyl-5-hydrogen-7-methoxy-naphthazarin （9）。통과 X －사선단정연사수차학정료화합물1화2적절대구형급존재형식。
The secondary metabolites of Fusarium solani 387 #from the South China Sea were studied. The structures of compounds were analyzed based on physical and chemical properties,and in comparison with the spectroscopic data with literatures published.Nine Fusarbin compounds were isolated from the mangrove endophytic fungus Fusarium solani 387 #from the South China Sea,and their structures were i-dentified as 5 (R)-deoxyfusarubin (1),5 (S)-deoxyfusarubin (2),3-methyl ether fusarubin (3), Fusarubin (4),Anhydrofusarabin (5 ),Anhydro-5-deoxyfusarubin (6 ),2-acetonyl-3-methyl-7-me-thoxy-naphthazarin (7),Javanicin (8 )and 2-acetonyl-3-methyl-5-hydrogen-7-methoxy-naphthazarin (9).The absolute configurations as well as the existing form of compound 1 and 2 were determined by the X-ray crystallography for the first time.