CAJ | 학술논문

目的：探索焦虑与2型糖尿病(T2DM)患者生活质量的关系，为有针对性地开展社区干预及提高患者生活质量提供依据。方法采用多阶段整群随机抽样方法，于2012年11月至2013年1月抽取徐州市4个县(市)区，在每个县(市)区内随机抽取8?10个村/小区，每村/小区内确诊的T2DM患者均为研究对象。使用自行设计的问卷、匹兹堡睡眠质量指数量表(PSQI)、焦虑自评量表(SAS)、抑郁自评量表(SDS)、糖尿病患者生活质量特异性量表(DSQL)进行面对面调查。将受试者按焦虑程度分为轻、中、重度组，比较各组焦虑与生活质量的关系差异。采用方差分析对多组间的均数进行比较，应用多元线性回归和Pearsonχ2检验分析焦虑与生活质量的关系。结果共调查776例糖尿病患者，58.89%(457/776)的患者有不同程度的焦虑，无、轻、中、重度焦虑患者的比例依次为41.11%(319/776)、49.61%(385/776)、7.99%(62/776)、1.29%(10/776)，生活质量总分依次为(40±9)、(47±11)、(52±15)和(65±13)分，差异有统计学意义(F=43.589，P＜0.05)。经相关分析显示，除社会关系维度(r=0.046， P＞0.05)以外，焦虑与患者DSQL总分、生理功能维度、心理精神维度、治疗维度均呈正相关(r=0.395、0.454、0.341、0.150，均P＜0.05)，其中焦虑与生活质量的生理维度相关性最强。校正年龄、性别、文化程度、婚姻、家庭收入、病程、并发症、血糖控制、睡眠质量、抑郁等因素后，焦虑与生活质量的回归系数为0.239，在众多因素中位居第一位。结论与其他因素比较，焦虑严重降低了糖尿病患者的生活质量。
목적：탐색초필여2형당뇨병(T2DM)환자생활질량적관계，위유침대성지개전사구간예급제고환자생활질량제공의거。방법채용다계단정군수궤추양방법，우2012년11월지2013년1월추취서주시4개현(시)구，재매개현(시)구내수궤추취8?10개촌/소구，매촌/소구내학진적T2DM환자균위연구대상。사용자행설계적문권、필자보수면질량지수량표(PSQI)、초필자평량표(SAS)、억욱자평량표(SDS)、당뇨병환자생활질량특이성량표(DSQL)진행면대면조사。장수시자안초필정도분위경、중、중도조，비교각조초필여생활질량적관계차이。채용방차분석대다조간적균수진행비교，응용다원선성회귀화Pearsonχ2검험분석초필여생활질량적관계。결과공조사776례당뇨병환자，58.89%(457/776)적환자유불동정도적초필，무、경、중、중도초필환자적비례의차위41.11%(319/776)、49.61%(385/776)、7.99%(62/776)、1.29%(10/776)，생활질량총분의차위(40±9)、(47±11)、(52±15)화(65±13)분，차이유통계학의의(F=43.589，P＜0.05)。경상관분석현시，제사회관계유도(r=0.046， P＞0.05)이외，초필여환자DSQL총분、생리공능유도、심리정신유도、치료유도균정정상관(r=0.395、0.454、0.341、0.150，균P＜0.05)，기중초필여생활질량적생리유도상관성최강。교정년령、성별、문화정도、혼인、가정수입、병정、병발증、혈당공제、수면질량、억욱등인소후，초필여생활질량적회귀계수위0.239，재음다인소중위거제일위。결론여기타인소비교，초필엄중강저료당뇨병환자적생활질량。
Objective To explore the relationship between anxiety and the quality of life in patients with type 2 diabetes mellitus (T2DM) to perform specific community prevention, and to provide reference to improve the quality of life in patients T2DM. Methods Total of 776 participants who lived in 32 villages/ communities of Xuzhou were enrolled with the multi-stage cluster random sampling method, and were investigated with a self-designed questionnaire, the Pittsburgh sleep quality index (PSQI), self rating Anxiety Scale (SAS), self rating Depression Scale (SDS) and the amount of specific quality of life in patients with diabetes mellitus (DSQL). The patients were divided into mild, moderate and severe anxiety groups. One-way analysis were used to analyze differences among several groups, Multiple linear regression and Pearson χ2 were used to analyze the association between anxiety and quality of life. Results Of the 776 enrolled diabetes mellitus patients, the prevalent rate of anxiety was 58.89%(457/776), the percentage of none, mild, moderate and severe anxiety were 41.11%(319/776), 49.61%(385/776), 7.99%(62/776), 1.29%(10/776)respectively. The scores of qualities of life in patients with type 2 diabetes with none, mild, moderate and severe anxiety were (40 ± 9), (47 ± 11), (52 ± 15) and (65 ± 13). There were significant differences between different groups (F=43.589, P<0.05). The correlation analysis between anxiety and total DSQL scale and components of DSQL showed that except for the social relationship dimension of DSQL(r=0.046, P>0.05), there were positive correlation between anxiety and total DSQL scale and the other dimensions of DSQL. The correlation between anxiety and total score of DSQL,physiological function dimension, psychological dimension and treatment dimension were 0.395, 0.454, 0.341, 0.150 (P<0.05, all above).The results showed that the correlation between anxiety and physical dimensions of DSQL was the strongest. After adjust for age, sex, culture degree, marriage, family income, course of disease, complication, blood glucose control, sleep quality, depression and so on, the regression coefficient of anxiety and quality of life was 0.239, ranked at the first factor in numerous oners. Conclusion Compared with other potential risk factors, the anxiety is the highest negatively related to the quality of life of patients with type 2 diabetes mellitus.