CAJ | 학술논문

三氯乙烯是用途广泛的有机溶剂和重要的工业原料。由于生产使用量大，废弃物处理不当，三氯乙烯已成为一种常见的环境污染物，因此有广泛的职业和环境暴露人群。三氯乙烯的职业和环境暴露可对多器官系统产生毒性作用。本文主要从流行病学研究、动物学试验以及毒性机制研究等几个方面对三氯乙烯的免疫毒性、生殖毒性、神经毒性和致畸作用等非致癌性毒性作用进行综述。
삼록을희시용도엄범적유궤용제화중요적공업원료。유우생산사용량대，폐기물처리불당，삼록을희이성위일충상견적배경오염물，인차유엄범적직업화배경폭로인군。삼록을희적직업화배경폭로가대다기관계통산생독성작용。본문주요종류행병학연구、동물학시험이급독성궤제연구등궤개방면대삼록을희적면역독성、생식독성、신경독성화치기작용등비치암성독성작용진행종술。
Trichloroethylene (TCE) is a widely used organic solvent and an important industrial material.Due to mass production and use,and improper waste disposal, TCE has become a common environmental contaminant, so there is a wide range of occupationally and environmentally exposed population.Occupational and environmental exposure to TCE can produce toxic effects on multiple organs and systems.This paper is a review of the immunotoxicity, reproductive toxicity, neurotoxicity, teratogenic effect and other non-carcinogenic toxic effects of TCE from the aspects of epidemiological study, experimental evidence on animals and toxic mechanisms.