CAJ | 학술논문

目的：分析数字减影血管造影下神经介入溶栓术治疗缺血性脑血管疾病的近期和远期疗效，以及并发症的发生情况。方法：选择88例接受治疗的缺血性脑血管疾病患者，根据发病时间和病变部位的不同将其分成对照组和观察组，每组44例。对照组患者行静脉溶栓治疗，观察组患者行动静脉联合神经介入溶栓术。结果：两组患者术后14 d，治疗总有效率观察组患者为95.45%，对照组患者为81.81%，两组相比差异有统计学意义(x2=4.062，P＜0.05)；观察组患者卒中复发率为6.82%，对照组患者卒中复发率为25.00%，两组相比差异有统计学意义(x2=5.436，P＜0.05)；术后观察组患者血管再通率为65.91%，对照组患者血管再通为40.91%，两组相比差异有统计学意义(x2=5.526，P＜0.05)。术后24 h及第7 d，观察组患者NIHSS评分显著低于对照组NIHSS评分，差异有统计学意义(t=2.784, t=2.673；P＜0.01)。结论：数字减影血管造影下神经介入溶栓治疗缺血性脑血管疾病的近期与远期疗效均较好，患者术后血管再通效果良好，术后生活质量显著改善。
목적：분석수자감영혈관조영하신경개입용전술치료결혈성뇌혈관질병적근기화원기료효，이급병발증적발생정황。방법：선택88례접수치료적결혈성뇌혈관질병환자，근거발병시간화병변부위적불동장기분성대조조화관찰조，매조44례。대조조환자행정맥용전치료，관찰조환자행동정맥연합신경개입용전술。결과：량조환자술후14 d，치료총유효솔관찰조환자위95.45%，대조조환자위81.81%，량조상비차이유통계학의의(x2=4.062，P＜0.05)；관찰조환자졸중복발솔위6.82%，대조조환자졸중복발솔위25.00%，량조상비차이유통계학의의(x2=5.436，P＜0.05)；술후관찰조환자혈관재통솔위65.91%，대조조환자혈관재통위40.91%，량조상비차이유통계학의의(x2=5.526，P＜0.05)。술후24 h급제7 d，관찰조환자NIHSS평분현저저우대조조NIHSS평분，차이유통계학의의(t=2.784, t=2.673；P＜0.01)。결론：수자감영혈관조영하신경개입용전치료결혈성뇌혈관질병적근기여원기료효균교호，환자술후혈관재통효과량호，술후생활질량현저개선。
Objective: To observe the short-term and long-term effect and complications of neurointerventional thrombolysis therapy for ischemic cerebrovascular diseases. Methods:Eighty eight patients with ischemic cerebrovascular diseases who received treatment in our hospital between July 2012 and September 2014 were selected as the research object, which were randomly divided into a control group and an observation group, each with 44 cases. Patients in the control group were treated with intravenous thrombolysis, whereas those in the observation group were given both intravenous and arterial thrombolysis therapy. Results:Fourteen days after the treatment, the total effective rate of treatment in the observation group was 95.45%, higher than that in the control group, which was 81.81%, and the difference was statistically significant (x2=4.062, P<0.05). The recurrence rate of stroke in the observation group was 6.82%, higher than the 25%in the observation group, with the difference being statistically significant (x2=5.436, P<0.05). In terms of blood vessel patency rate after the treatment, the observation group was 65.91%, higher than that of the control group, which was 40.91%, and the difference was statistically significant (x2=5.526, P<0.05). The NIHSS scores 1 day and 7 days after the treatment in the observation group were significantly less than those in the control group, and the difference was statistically significant (t=2.784, t=2.673;P<0.01). Conclusion:Neurointerventional thrombolysis is with significant short-term and long-term effect in the treatment of ischemic cerebrovascular diseases, with better postoperative blood vessel patency and improved quality of life.