实用药物与临床
實用藥物與臨床
실용약물여림상
Practical Pharmacy and Clinical Remedies
2015年
9期
1048-1051
,共4页
严重创伤%多器官功能障碍综合征%血必净
嚴重創傷%多器官功能障礙綜閤徵%血必淨
엄중창상%다기관공능장애종합정%혈필정
Severe trauma%Multiple organ dysfunction syndrome%Xuebijing
目的 评价血必净注射液在严重外伤并发多器官功能障碍综合征( MODS)患者治疗中的价值.方法 选择2011年11月至2014年9月由严重创伤导致的MODS在外科ICU病房的患者共50 例,随机分为2组:治疗组(加用血必净注射液)26例,对照组(常规治疗)24例. 观察血必净治疗后患者的平均动脉压、尿量、氧合指数、血小板及受累器官评分变化情况. 结果 血必净治疗后患者平均动脉压、尿量增加,氧合指数升高,血小板升高,受累器官评分改善,与对照组比较差异有统计学意义(P<0.05). 结论 血必净注射液可以辅助治疗由多发创伤等引起的MODS,在呼吸、循环及凝血方面较对照组有明显改善,临床试验中未发现明显的不良反应,具有明显推广价值.
目的 評價血必淨註射液在嚴重外傷併髮多器官功能障礙綜閤徵( MODS)患者治療中的價值.方法 選擇2011年11月至2014年9月由嚴重創傷導緻的MODS在外科ICU病房的患者共50 例,隨機分為2組:治療組(加用血必淨註射液)26例,對照組(常規治療)24例. 觀察血必淨治療後患者的平均動脈壓、尿量、氧閤指數、血小闆及受纍器官評分變化情況. 結果 血必淨治療後患者平均動脈壓、尿量增加,氧閤指數升高,血小闆升高,受纍器官評分改善,與對照組比較差異有統計學意義(P<0.05). 結論 血必淨註射液可以輔助治療由多髮創傷等引起的MODS,在呼吸、循環及凝血方麵較對照組有明顯改善,臨床試驗中未髮現明顯的不良反應,具有明顯推廣價值.
목적 평개혈필정주사액재엄중외상병발다기관공능장애종합정( MODS)환자치료중적개치.방법 선택2011년11월지2014년9월유엄중창상도치적MODS재외과ICU병방적환자공50 례,수궤분위2조:치료조(가용혈필정주사액)26례,대조조(상규치료)24례. 관찰혈필정치료후환자적평균동맥압、뇨량、양합지수、혈소판급수루기관평분변화정황. 결과 혈필정치료후환자평균동맥압、뇨량증가,양합지수승고,혈소판승고,수루기관평분개선,여대조조비교차이유통계학의의(P<0.05). 결론 혈필정주사액가이보조치료유다발창상등인기적MODS,재호흡、순배급응혈방면교대조조유명현개선,림상시험중미발현명현적불량반응,구유명현추엄개치.
Objective To evaluate the therapeutic value of Xuebijing injection in severe trauma patients with multiple organ dysfunction syndrome ( MODS) . Methods 50 MODS patients in surgical ICU ward of our hospital from November 2011 to September 2014 were chose and randomly divided into 2 groups:treatment group ( treated with Xuebijing injection,n=26) and control group (conventional treatment,n=24). Mean arterial pressure,urine volume, oxygenation index,platelet count and involved organs of patients in the two group were observed. Results The mean arterial pressure and urine volume of treatment group were increased,oxygenation index and the platelet count were in-creased,the involved organs were improved,there were significant differences compared with those of control group ( P<0.05). Conclusion Xuebijing injection can assist in the treatment of multiple trauma caused by MODS,the respira-tory,circulatory and blood coagulation are significantly improved than those of control group. No obvious adverse reac-tion is found in clinical trial,which has obvious promotion value.
