CAJ | 학술논문

目的：分析妊娠剧吐(hyperemesis gravidamm)患者甲状腺功能的变化规律。方法检测40例孕16w内妊娠剧吐患者及40例孕16w内正常孕妇血清游离三碘甲状腺原氨酸(FT3)、血清游离甲状腺素(FT4)、血清促甲状腺素(TSH)、甲状腺球蛋白抗体(TgAb)、甲状腺过氧化物酶抗体(TPOAb)浓度。结果妊娠剧吐组与正常妊娠组比较,血清FT3、FT4、TgAb、TPOAb浓度升高,差异有显著意义(<0.01)；血清TSH浓度降低,差异有显著意义(<0.01)。两组孕妇,TPOAb阳性率差别无统计学意义(>0.05)。结论妊娠剧吐患者甲状腺功能呈现亢进改变,但两组孕妇甲状腺自身抗体阳性率无显著性差异。
목적：분석임신극토(hyperemesis gravidamm)환자갑상선공능적변화규률。방법검측40례잉16w내임신극토환자급40례잉16w내정상잉부혈청유리삼전갑상선원안산(FT3)、혈청유리갑상선소(FT4)、혈청촉갑상선소(TSH)、갑상선구단백항체(TgAb)、갑상선과양화물매항체(TPOAb)농도。결과임신극토조여정상임신조비교,혈청FT3、FT4、TgAb、TPOAb농도승고,차이유현저의의(<0.01)；혈청TSH농도강저,차이유현저의의(<0.01)。량조잉부,TPOAb양성솔차별무통계학의의(>0.05)。결론임신극토환자갑상선공능정현항진개변,단량조잉부갑상선자신항체양성솔무현저성차이。
Objective To analyse the change of thyroid function generating in hyperemesis gravidarum women.Methods Measured theconcentrations of free thyroxine 3 (FT3),free thyroxine 4(FT4), thyroid stimulatinghormone (TSH),Thyroglobulinantibody (TgAb),Thyroid Peroxidase Antibody (TPOAb)of the serum of 40 hyperemesis gravidarum women within16 gestational weeks and 40 normal pregnant women within16 gestational weeks.Results The serum concentrations of FT3,FT4,TgAb,TPOAb in hyperemesis gravidarum pregnant women were higher than those of in normal pregnant women and the dif erences were statistical y significant( <O.01);the concentrations of TSH in hyperemesis gravidarum women were lower than those of in normal pregnant women and the dif erence was significant ( <0.01).The positive rate of TgAb and TPOAb in two groups showed no statistical y significant ( ﹥0.05). Conclusion Hyperemesis gravidarum women showed the change of biochemistric indeices of hyperthyroidism,but the positive rate of TgAb and TPOAb in two groups had no statistical y significant dif erence.