CAJ | 학술논문

近年来学者们对于小气道疾病方面的研究逐渐深入和增加，目前认为除了C O PD和支气管哮喘（简称哮喘）可累及小气道之外，小气道疾病亦有许多其他的病因。小气道位于外周、直径小于2 mm。小气道疾病肺功能以FEF25％‐75％、FEF50％、FEF25％下降为特征，胸部HRCT可表现为小叶中心性结节、支气管壁增厚、支气管扩张、“马赛克”征、“空气潴留”征，病理示中性粒细胞、淋巴细胞、浆细胞等多种炎性细胞的浸润，某些小气道疾病治疗效果较好：如戒烟治疗呼吸性细支气管炎并间质性肺疾病、大环内酯类抗生素治疗弥漫性泛细支气管炎，但较多小气道疾病仍无较好的治疗方法。
근년래학자문대우소기도질병방면적연구축점심입화증가，목전인위제료C O PD화지기관효천（간칭효천）가루급소기도지외，소기도질병역유허다기타적병인。소기도위우외주、직경소우2 mm。소기도질병폐공능이FEF25％‐75％、FEF50％、FEF25％하강위특정，흉부HRCT가표현위소협중심성결절、지기관벽증후、지기관확장、“마새극”정、“공기저류”정，병리시중성립세포、림파세포、장세포등다충염성세포적침윤，모사소기도질병치료효과교호：여계연치료호흡성세지기관염병간질성폐질병、대배내지류항생소치료미만성범세지기관염，단교다소기도질병잉무교호적치료방법。
Reasearchers have published lots of papers about small airway diseases recent years .So far ,it is think that small airway diseases results from many other diseases except chronic obstructive pulmonary disease and bronchial asthma (asthma) .Small airways are in the periphery and its diameter are smaller than 2 mm .Small airway diseases′s characters are as follows:FEF25%‐75% ,FEF50% ,FEF25%decreasing in pulmonary function test ,centrilobular nodules ,thicked wall ,bronchiectasis ,mosaic pattern of attenuation ,air trapping in HRCT ,neutrophil ,lymphocyte ,plasmocyte infiltrated in pathology ,some diseases can relieve well after treatment :respiratory bronchiolitis‐associated interstitial lung disease after smoking cessation ,diffuse panbronchiolitis with use of macrolide antibiotics ,however ,many others without appropriate regimens .