CAJ | 학술논문

目的：分析肺栓塞（pulmonary embolism ，PE）患者临床症状、临床危险因素、临床评分及生化指标，探讨各指标在PE诊断中的意义。方法回顾性分析81例确诊为PE患者的临床症状、临床危险因素、简化的Wells和Geneva评分。比较分析PE组和非PE组D‐二聚体（DD）、纤维蛋白原（FIB）、C反应蛋白（CRP）指标的差异。结果 PE组患者临床症状中以呼吸困难为主；危险因素中深静脉血栓形成（VTD）病史最多占71％，而无明显危险因素者位居第二，高达27％；简化的Wells和Geneva评分的敏感度分别为70％和72％；PE组DD、FIB、CRP值高于非PE组，差异具有统计学意义。结论对于疑为PE或者是无明显危险因素但无法用其他疾病解释的呼吸困难患者，应联合临床评分和生化指标检测，降低PE漏诊率。
목적：분석폐전새（pulmonary embolism ，PE）환자림상증상、림상위험인소、림상평분급생화지표，탐토각지표재PE진단중적의의。방법회고성분석81례학진위PE환자적림상증상、림상위험인소、간화적Wells화Geneva평분。비교분석PE조화비PE조D‐이취체（DD）、섬유단백원（FIB）、C반응단백（CRP）지표적차이。결과 PE조환자림상증상중이호흡곤난위주；위험인소중심정맥혈전형성（VTD）병사최다점71％，이무명현위험인소자위거제이，고체27％；간화적Wells화Geneva평분적민감도분별위70％화72％；PE조DD、FIB、CRP치고우비PE조，차이구유통계학의의。결론대우의위PE혹자시무명현위험인소단무법용기타질병해석적호흡곤난환자，응연합림상평분화생화지표검측，강저PE루진솔。
Objective To analysis clinical symptom ,clinical risk factors ,clinical prediction rules and biochemical indexes of 81 patients with pulmonary embolism and to study the significance of these in diagnosis of pulmonary embolism (PE) .Methods Retrospective analysis of clinical symptom ,clinical risk factors ,revised Wells rule and Geneva score of 81 patients with PE .Comparative analysis of D‐dimer (DD) ,fibrinogen (FIB) and C reactive protein (CRP) between PE group and non PE group .Results The main clinical symptom of patients in PE group was dyspnea .Deep venous thrombosis (VTD) history accounts for up to 71% in risk factors ,but no obvious risk factors were ranked second ,up to 27% .The sensitivity of revised Wells rule and Geneva score was 70% and 72% respectively .DD ,FIB and CRP value in PE group was higher than non PE group ,which has statistical significance .Conclusions For the patients who is suspected PE or has dyspnea but not with other disease and significant risk factors ,should combined with detection of clinical score and biochemical indexes ,which can reduce the misdiagnosis rate of PE .