CAJ | 학술논문

目的：报道1例急性非淋巴细胞白血病患者异基因造血干细胞移植后发生巨细胞病毒（CM V ）合并偏肺病毒（hM PV ）感染病例，并监测其hM PV排毒时间。方法定期采集患者咽拭子和痰样本，采用实时荧光定量聚合酶链反应的方法测定样本中hM PV的拷贝数。结果该患者的咽拭子和痰中hM PV持续阳性至发病后第41天。结论免疫功能低下患者感染hM PV可长期无症状排毒，临床医生需要给予动态监测，并做好预防院内感染的措施。
목적：보도1례급성비림파세포백혈병환자이기인조혈간세포이식후발생거세포병독（CM V ）합병편폐병독（hM PV ）감염병례，병감측기hM PV배독시간。방법정기채집환자인식자화담양본，채용실시형광정량취합매련반응적방법측정양본중hM PV적고패수。결과해환자적인식자화담중hM PV지속양성지발병후제41천。결론면역공능저하환자감염hM PV가장기무증상배독，림상의생수요급여동태감측，병주호예방원내감염적조시。
Objective To report the occurrence of lower respiratory tract disease associated with cytomegalovirus and hMPVcoinfection in a patient after allogeneic hematopoietic stem cell transplantation (HSCT) for acute non‐lymphocytic leukemia ,and to monitor the shedding time of hMPV .Methods Patient’s oropharyngeal swab and sputum samples periodically were collected ,hMPV copies in these sampes were determined by real‐time polymerase chain reaction .Results Repeat oropharyngeal swab and sputum samples was positive for hMPV until 41th day after onset .Conclusions Immunocompromised patients infected with hMPV will show as prolong viral shedding with asymptomatic and the clinician must pay more attention on immunocompromised patients for viral shedding ,and prevent cross infection in the w ard .