国际免疫学杂志
國際免疫學雜誌
국제면역학잡지
International Journal of Immunology
2015年
5期
496-500
,共5页
IL-6%原发性肝细胞癌
IL-6%原髮性肝細胞癌
IL-6%원발성간세포암
Interleukin-6%Primary hepatocellular carcinoma
白细胞介素-6(IL-6)是一种重要的炎症因子,其可通过多种机制调节细胞的生长、分化与功能作用.近来有研究表明,IL-6与原发性肝细胞癌(HCC,简称肝癌)的发生发展相关.肝癌患者血清中IL-6明显升高,并且其水平与肿瘤的演变、转归及预后有着一定关系.还有学者发现,联合监测IL-6及其他肿瘤指标可明显提高肝癌诊断的灵敏度与特异度.因此,深入研究IL-6与肝癌的关系,将有助于提高肝癌的临床早期诊断率,并可为其病情观察、疗效监测及预后评估等提供新的思路.
白細胞介素-6(IL-6)是一種重要的炎癥因子,其可通過多種機製調節細胞的生長、分化與功能作用.近來有研究錶明,IL-6與原髮性肝細胞癌(HCC,簡稱肝癌)的髮生髮展相關.肝癌患者血清中IL-6明顯升高,併且其水平與腫瘤的縯變、轉歸及預後有著一定關繫.還有學者髮現,聯閤鑑測IL-6及其他腫瘤指標可明顯提高肝癌診斷的靈敏度與特異度.因此,深入研究IL-6與肝癌的關繫,將有助于提高肝癌的臨床早期診斷率,併可為其病情觀察、療效鑑測及預後評估等提供新的思路.
백세포개소-6(IL-6)시일충중요적염증인자,기가통과다충궤제조절세포적생장、분화여공능작용.근래유연구표명,IL-6여원발성간세포암(HCC,간칭간암)적발생발전상관.간암환자혈청중IL-6명현승고,병차기수평여종류적연변、전귀급예후유착일정관계.환유학자발현,연합감측IL-6급기타종류지표가명현제고간암진단적령민도여특이도.인차,심입연구IL-6여간암적관계,장유조우제고간암적림상조기진단솔,병가위기병정관찰、료효감측급예후평고등제공신적사로.
Serum interleukin-6 (IL-6) is an important inflammatory factor regulating cell growth,differentiation and function.Recent studies have shown that IL-6 is one of the causes for the development of hepatocellular carcinoma (HCC).In patients with HCC,IL-6 is significantly increased and related with the prognosis of HCC.Some researchers found that monitoring IL-6 combining with other tumor markers can obviously improve the sensitivity and specificity for the early diagnosis of HCC.Therefore,further study on the relationship between IL-6 and HCC will provide new strategy for the early diagnosis and the evaluation on therapeutic effect and prognosis of HCC.
