临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
Chinese Journal of Clinical Rational Drug Use
2015年
29期
16-17
,共2页
咪喹莫特%传染性软疣%干扰素%他扎罗汀
咪喹莫特%傳染性軟疣%榦擾素%他扎囉汀
미규막특%전염성연우%간우소%타찰라정
5％ imiquimod cream%Mollusecumcontagiosum%Recombinant human interferon alpha 2b cream%Tazaro-tene gel
目的：观察5%咪喹莫特软膏治疗传染性软疣的临床疗效及安全性。方法选取2014年5~10月门诊确诊的传染性软疣患者90例，随机分为治疗组和对照组各45例。治疗组予5%咪喹莫特软膏治疗，对照组予重组人干扰素α-2b乳膏治疗并加用他扎罗汀凝胶。2组治疗期间均每周复诊1次，连续观察4周，疗程结束时判定疗效。结果治疗组第1、2、3、4周有效率均优于对照组，差异有统计学意义（ P<0.05）。结论5%咪喹莫特乳膏治疗传染性软疣，疗效确切，不良反应小，安全性高，值得临床推广应用。
目的：觀察5%咪喹莫特軟膏治療傳染性軟疣的臨床療效及安全性。方法選取2014年5~10月門診確診的傳染性軟疣患者90例，隨機分為治療組和對照組各45例。治療組予5%咪喹莫特軟膏治療，對照組予重組人榦擾素α-2b乳膏治療併加用他扎囉汀凝膠。2組治療期間均每週複診1次，連續觀察4週，療程結束時判定療效。結果治療組第1、2、3、4週有效率均優于對照組，差異有統計學意義（ P<0.05）。結論5%咪喹莫特乳膏治療傳染性軟疣，療效確切，不良反應小，安全性高，值得臨床推廣應用。
목적：관찰5%미규막특연고치료전염성연우적림상료효급안전성。방법선취2014년5~10월문진학진적전염성연우환자90례，수궤분위치료조화대조조각45례。치료조여5%미규막특연고치료，대조조여중조인간우소α-2b유고치료병가용타찰라정응효。2조치료기간균매주복진1차，련속관찰4주，료정결속시판정료효。결과치료조제1、2、3、4주유효솔균우우대조조，차이유통계학의의（ P<0.05）。결론5%미규막특유고치료전염성연우，료효학절，불량반응소，안전성고，치득림상추엄응용。
Objective To observe the clinical efficacy and safety of 5% imiquimod cream in the treatment of mollus-cumcontagiosum. Methods 90 cases of molluscumcontagiosum patients,were randomly divided into treatment group and con-trol group,45 cases in each. The treatment group treated with 5% imiquimod cream,The control group treated with recombinant human interferon alpha 2b cream and tazarotene gel. The 2 groups were reviewed 1 times a week,for 4 weeks,the efficacy was determined at the end of the course. Results The effective rate of 1st,2nd,3rd and 4thweeks in the treatment group were bet-ter than those in the control group,the difference was statistically significant(P<0. 05). Conclusion The clinical effect of 5% Imiquimod Cream treating molluscumcontagiosum,less adverse reaction,high safety. Worthy of clinical popularization and application.
