CAJ | 학술논문

目的：从疾病流行病学负担和经济负担两个方面出发，探讨安徽省宣城市精神分裂症疾病负担情况。方法收集2010—2012年于宣城市人民医院、宣城市中心医院和宣城市第四人民医院（宣城市精神病医院）住院、符合纳入与排除标准的全部精神分裂症患者316例为研究对象。计算并比较其疾病流行病学负担指标〔伤残调整寿命年（ DALYs）、因早死所致的寿命损失年（ YLLs）、疾病所致伤残引起的健康寿命损失年（ YLDs）〕和经济负担指标（直接经济负担、间接经济负担）。结果2010—2012年男、女性精神分裂症患者YLDs均大于YLLs；男性精神分裂症患者YLDs、 YLLs均大于女性。2011、2012年次均直接经济负担高于2010年（ q＝2.77， P＜0.05； q＝3.11， P＜0.05）；2012年次均直接经济负担高于2011年（q＝2.77， P＜0.05）。2010—2012年男性精神分裂症患者次均直接经济负担高于女性（ P＜0.05）。2010—2012年精神分裂症患者间接经济负担年增长速度为24.21％。2010—2012年男性精神分裂症患者间接经济负担高于女性。结论宣城市2010—2012年精神分裂症疾病负担巨大，且疾病流行病学负担和经济负担均呈逐年上升趋势，提示国家、社会及每个公民均应给予关注和支持，多部门应采取相应措施，遏制宣城市精神分裂症疾病负担进一步加重。
목적：종질병류행병학부담화경제부담량개방면출발，탐토안휘성선성시정신분렬증질병부담정황。방법수집2010—2012년우선성시인민의원、선성시중심의원화선성시제사인민의원（선성시정신병의원）주원、부합납입여배제표준적전부정신분렬증환자316례위연구대상。계산병비교기질병류행병학부담지표〔상잔조정수명년（ DALYs）、인조사소치적수명손실년（ YLLs）、질병소치상잔인기적건강수명손실년（ YLDs）〕화경제부담지표（직접경제부담、간접경제부담）。결과2010—2012년남、녀성정신분렬증환자YLDs균대우YLLs；남성정신분렬증환자YLDs、 YLLs균대우녀성。2011、2012년차균직접경제부담고우2010년（ q＝2.77， P＜0.05； q＝3.11， P＜0.05）；2012년차균직접경제부담고우2011년（q＝2.77， P＜0.05）。2010—2012년남성정신분렬증환자차균직접경제부담고우녀성（ P＜0.05）。2010—2012년정신분렬증환자간접경제부담년증장속도위24.21％。2010—2012년남성정신분렬증환자간접경제부담고우녀성。결론선성시2010—2012년정신분렬증질병부담거대，차질병류행병학부담화경제부담균정축년상승추세，제시국가、사회급매개공민균응급여관주화지지，다부문응채취상응조시，알제선성시정신분렬증질병부담진일보가중。
Objective To investigate the disease burden of schizophrenia in Xuancheng of Anhui Province from the aspects of epidemiological burden and economic burden.Methods 316 schizophrenia patients who accorded with inclusion and exclusion criteria and were admitted into Xuancheng People′s Hospital, Xuancheng Central Hospital and the Fourth Hospital of Xuancheng ( Xuancheng Psychiatric Hospital ) from 2010 to 2012 were enrolled in the study.The indexes of epidemiological burden ( DALYs, YLLs and YLDs ) and the indexes of economic burden ( direct economic burden and indirect economic burden) were calculated and compared.Results From 2010 to 2012, the YLDs of male and female schizophrenia patients were higher than YLLs; male schizophrenia patients had higher YLDs and YLLs than female schizophrenia patients.The average direct economic burden in 2011 and 2012 was higher than that in 2010 ( q=2.77, P<0.05; q=3.11, P<0.05 ); the average direct economic burden in 2012 was higher than that in 2011 ( q=2.77, P<0.05) .From 2010 to 2012, the average direct economic burden of male schizophrenia patients was higher than that of male schizophrenia patients ( P<0.05 ) .From 2010 to 2012, the annual increase rate of the indirect economic burden of male schizophrenia patients was 24.21%.From 2010 to 2012, the indirect economic burden of male schizophrenia patients was higher than female schizophrenia patients .Conclusion From 2010 to 2012, there was enormous disease burden of schizophrenia in Xuancheng , and the epidemiological burden and economic burden were increasing year by year.We suggest that every citizen should give attention and support in this aspect , and relevant sectors should take corresponding measures , in order to stop the disease burden of schizophrenia from aggravating.