CAJ | 학술논문

目的：探讨 Ia2～IIa2期宫颈癌患者盆腔淋巴结转移的高危因素。方法对337例 Ia2～IIa2期宫颈癌住院手术患者的临床病理资料进行回顾性分析，研究盆腔淋巴结转移的相关因素。结果盆腔淋巴结总转移率为11．87％，转移部位以闭孔区淋巴结和髂内淋巴结最为常见。多因素分析提示肿瘤浸润深度、肿瘤大小、脉管癌栓和宫旁浸润是发生淋巴结转移的独立危险因素，其 OR 值（95％CI）分别为3．464（1．502～7．985）、4．316（1．164～7．833）、6．167（2．592～14．674）和8．507（1．966～36．808）。结论肿瘤浸润深度≥2／3、肿瘤大小≥4 cm、脉管癌栓阳性和宫旁浸润阳性易发生宫颈癌淋巴结转移。
목적：탐토 Ia2～IIa2기궁경암환자분강림파결전이적고위인소。방법대337례 Ia2～IIa2기궁경암주원수술환자적림상병리자료진행회고성분석，연구분강림파결전이적상관인소。결과분강림파결총전이솔위11．87％，전이부위이폐공구림파결화가내림파결최위상견。다인소분석제시종류침윤심도、종류대소、맥관암전화궁방침윤시발생림파결전이적독립위험인소，기 OR 치（95％CI）분별위3．464（1．502～7．985）、4．316（1．164～7．833）、6．167（2．592～14．674）화8．507（1．966～36．808）。결론종류침윤심도≥2／3、종류대소≥4 cm、맥관암전양성화궁방침윤양성역발생궁경암림파결전이。
Objective To investigate the metastatic risk factors of pelvic lymph nodes in patients with cervical carcinoma of stage Ia2 and IIa2.Methods The clinic opathologicparameters in 337 patients with stage Ia2 -IIa2 cervical carcinoma were retrospectively analyzed,and were studied the related factors of pelvic lymph node metastasis.Results The lymph nodes metastasis rate was 11.87%,with the obturator and internal iliaclymph nodes mostly involved.Multivariate analysis showed that the myometrial invasion,size of tumor,lymph -vascular space involvement and utero -tissue infiltration were major risk factors.The OR value and 95%CI were 3.464(1.502 -7.985)、4.316 (1.164 -7.833)、6.167 (2.592 -14.674)和 8.507(1.966 -36.808)respectively.Conclusion The myometrial invasion≥ 2 /3,size of tumor≥ 4 cm, lymph -vascular space involvement and utero -tissue infiltration positive lymph node metastasis of cervical cancer are easy to occur.