CAJ | 학술논문

目的：采用多普勒超声观察中老年原发性高血压患者血同型半胱氨酸(Hcy)水平增高对心脏结构的影响。方法将122例符合纳入标准的原发性高血压患者根据 Hcy水平分为 Hcy正常组、Hcy增高组,所有对象均检测 Hcy,并进行心脏超声检测。结果 Hcy与室间隔厚度(IVS)、室间隔厚度/左室后壁厚度(IVS/ PWT)值呈正相关(r值分别为0.267、0.266,P<0.01)。Hcy增高组 IVS、IVS/ PWT值较 Hcy正常组明显增大(P<0.05)。结论血 Hcy水平增高可能促使高血压患者左心室肥厚。
목적：채용다보륵초성관찰중노년원발성고혈압환자혈동형반광안산(Hcy)수평증고대심장결구적영향。방법장122례부합납입표준적원발성고혈압환자근거 Hcy수평분위 Hcy정상조、Hcy증고조,소유대상균검측 Hcy,병진행심장초성검측。결과 Hcy여실간격후도(IVS)、실간격후도/좌실후벽후도(IVS/ PWT)치정정상관(r치분별위0.267、0.266,P<0.01)。Hcy증고조 IVS、IVS/ PWT치교 Hcy정상조명현증대(P<0.05)。결론혈 Hcy수평증고가능촉사고혈압환자좌심실비후。
Objective To observe the effects of elevated serum homocysteine(Hcy)level on cardiac structure in middle old aged pa-tients with hypertension.Methods One hundred and twenty two patients were enrol ed and divided into the control group and hyper-homocysteinemia group by serum Hcy level .The parameters of the ultrasound cardiogram of the heart were detected.Results A sig-nificant positive correlation was observed between the Hcy and interventricular septal(IVS),IVS/posterior wal thickness (PWT)(r= 0.267 and 0.266,P<0.01).IVS and IVS/PWT in hyperhomocysteinemia group were higher than that in control group(P<0.05).Conclusion Elevated Hcy may be involved in the hypertrophy of the left ventricle of hypertension.