CAJ | 학술논문

目的了解盐碘含量调整后浙江省人群碘营养水平及甲状腺病情情况.方法 2013年4-6月,采用人口比例概率法在浙江省31个县区抽取1 650名学龄儿童与620名孕妇作为调查对象,对学龄儿童进行家庭食用盐盐碘含量检测、尿碘含量检测以及甲状腺B超检查,对孕妇进行尿碘含量检测.盐碘含量检测使用直接滴定法;尿碘含量检测使用过硫酸铵消化-砷铈催化分光光度法.结果盐碘含量调整后浙江省碘盐覆盖率为93.20％(1 521/1 632),合格碘盐食用率为89.71％(1 464/1 632);学龄儿童尿碘中位数为178.40μg/L,孕妇尿碘中位数为127.23 μg/L;学龄儿童甲状腺肿大率为5.27％(87/1 650),甲状腺容积中位数为3.45 ml;碘盐含量调整后,8、9、10岁组学龄儿童甲状腺容积P97分位数分别为4.76、5.29和6.36 ml,均高于推荐标准(WS 276-2007)的4.5、5.0和6ml;并未发现甲状腺容积、甲状腺肿大与尿碘水平的相关关系.结论盐碘含量调整后,浙江省人群尿碘水平回落到适宜水平,说明本次盐碘含量的调整是及时、合适的,但孕妇等特需人群碘营养水平不足的问题应引起注意.
목적 료해염전함량조정후절강성인군전영양수평급갑상선병정정황.방법 2013년4-6월,채용인구비례개솔법재절강성31개현구추취1 650명학령인동여620명잉부작위조사대상,대학령인동진행가정식용염염전함량검측、뇨전함량검측이급갑상선B초검사,대잉부진행뇨전함량검측.염전함량검측사용직접적정법;뇨전함량검측사용과류산안소화-신시최화분광광도법.결과 염전함량조정후절강성전염복개솔위93.20％(1 521/1 632),합격전염식용솔위89.71％(1 464/1 632);학령인동뇨전중위수위178.40μg/L,잉부뇨전중위수위127.23 μg/L;학령인동갑상선종대솔위5.27％(87/1 650),갑상선용적중위수위3.45 ml;전염함량조정후,8、9、10세조학령인동갑상선용적P97분위수분별위4.76、5.29화6.36 ml,균고우추천표준(WS 276-2007)적4.5、5.0화6ml;병미발현갑상선용적、갑상선종대여뇨전수평적상관관계.결론 염전함량조정후,절강성인군뇨전수평회락도괄의수평,설명본차염전함량적조정시급시、합괄적,단잉부등특수인군전영양수평불족적문제응인기주의.
Objective To find out the status of iodine nutrition and the goiter of population in Zhejiang Province after adjustment of salt iodine concentration.Methods From April to June 2013,the probability proportionate to size sampling method was applied in 31 countries in Zhejiang Province to select 1 650 school-age children aged 8-10 to examine thyroid by B ultrasound,to collect urine and salt samples,and to test the iodine level using the colorimetric titration method and the spectrophotometer method.Six hundred and twenty pregnant women were selected to collect urine samples and urinary iodine was tested by the spectrophotometer method.Results The coverage rate of iodized salt and the consumption rate of qualified iodized salt in Zhejiang Province after adjustment of salt iodine concentration were 93.20％ (1 521/1 632) and 89.71％ (1 464/1 632),respectively;and the medians urinary iodine in children and pregnant women were 178.40 μg/L and 127.23 μg/L,respectively;and the goiter and median thyroid volume were 5.27％ (87/1 650) and 3.45 ml,respectively;the P97 thyroid volume of children in Zhejiang Province in the 8,9 and 10 years old groups (4.76,5.29,6.36 ml) were higher than those (4.5,5.0,6.0 ml) in the thyroid volume reference (WS 276-2007);and the correlations between thyroid volume,goiter and urinary iodine were not found.Conclusions After adjustment of salt iodine concentration,the status of iodine nutrition in Zhejiang Province in general is down to optimum level,which indicates that it is appropriate for this adjustment,but the level of iodine nutrition in pregnant women is less than appropriate,which should be pay attention to.