中国药师
中國藥師
중국약사
China Pharmacist
2015年
10期
1705-1707
,共3页
毛丹%毛秀红%吴弢%季申
毛丹%毛秀紅%吳弢%季申
모단%모수홍%오도%계신
安胃疡胶囊%质量标准%甘草查尔酮甲%薄层色谱法%高效液相色谱法
安胃瘍膠囊%質量標準%甘草查爾酮甲%薄層色譜法%高效液相色譜法
안위양효낭%질량표준%감초사이동갑%박층색보법%고효액상색보법
Anweiyang capsules%Quality standard%Licochalcone A%TLC%HPLC
目的:研究修订安胃疡胶囊的质量标准. 方法:采用薄层色谱法对制剂中甘草进行定性测定;采用高效液相色谱法对甘草查尔酮甲进行定量测定,采用C18柱,流动相为乙腈-0. 1%磷酸溶液(40: 60),检测波长为376 nm. 结果: 薄层色谱斑点清晰,分离度好,阴性无干扰. 含量测定中甘草查尔酮甲在25. 563~1 533. 798 ng的范围内线性关系良好(r=0. 999 9),加样回收率为99. 8%(n=9). 结论:该法简便、准确,进一步完善了安胃疡胶囊的质量标准,可作为质量控制标准.
目的:研究脩訂安胃瘍膠囊的質量標準. 方法:採用薄層色譜法對製劑中甘草進行定性測定;採用高效液相色譜法對甘草查爾酮甲進行定量測定,採用C18柱,流動相為乙腈-0. 1%燐痠溶液(40: 60),檢測波長為376 nm. 結果: 薄層色譜斑點清晰,分離度好,陰性無榦擾. 含量測定中甘草查爾酮甲在25. 563~1 533. 798 ng的範圍內線性關繫良好(r=0. 999 9),加樣迴收率為99. 8%(n=9). 結論:該法簡便、準確,進一步完善瞭安胃瘍膠囊的質量標準,可作為質量控製標準.
목적:연구수정안위양효낭적질량표준. 방법:채용박층색보법대제제중감초진행정성측정;채용고효액상색보법대감초사이동갑진행정량측정,채용C18주,류동상위을정-0. 1%린산용액(40: 60),검측파장위376 nm. 결과: 박층색보반점청석,분리도호,음성무간우. 함량측정중감초사이동갑재25. 563~1 533. 798 ng적범위내선성관계량호(r=0. 999 9),가양회수솔위99. 8%(n=9). 결론:해법간편、준학,진일보완선료안위양효낭적질량표준,가작위질량공제표준.
Objective:To improve the quality standard for Anweiyang capsules. Methods: TLC was used to identify Glycyrrhiza inflata Bat. Licochalcone A was determined by RP-HPLC. Using a C18 Column, the mobile phase consisted of acetonitrile-0. 1% phos-phoric acid(40:60), and the detection wavelength was at 376 nm. Results:The herb could be identified by TLC. For licochalcone A, the linear range was from 25. 563 to 1 533. 798 ng, and the average recovery was 99. 8%(n=9). Conclusion:The method is simple and accurate, which can be used to improve and control the quality of Anweiyang capsules.
