皖南医学院学报
皖南醫學院學報
환남의학원학보
Acta Academiae Medicinae Wannan
2015年
5期
479-482
,共4页
超声心动图%实时三维超声%糖尿病%构型%标化
超聲心動圖%實時三維超聲%糖尿病%構型%標化
초성심동도%실시삼유초성%당뇨병%구형%표화
echocardiography%real-time three-dimensional ultrasound%diabetes mellitus%geometry%standardization
目的：通过体表面积对左心构型超声指标进行标化，观察标化前、后各项指标在空腹血糖受损组及糖尿病组的变化；并将标化前后指标对比分析，初步探讨标化前、后指标反映左心构型变化的敏感性。方法：于我院2012年1月～2013年12月门诊及住院糖尿病病人中选择80例患者，按1999年WHO规定的糖尿病的诊断标准分成两组：空腹血糖受损组及糖尿病组。于我院健康体检中心选择20例研究对象为正常对照组。心电触发二维切面超声于心脏舒张期末测量超声参数，将这些参数用体表面积标化，一方面观察标化前后各项指标随血糖升高发生的变化，另一方面将标化前后指标对比，通过统计学处理分析，观察标化前后指标在反映血糖升高对左心构型的改变方面的敏感性和稳定性。结果：上述标化前后各项指标均值在空腹血糖受损组及糖尿病组逐渐增大，其中标化前空腹血糖受损组各项指标与正常对照组之间的差异无显著性（P＞0．05），标化后与正常对照组之间的差异有显著性（P均＜0．01）；糖尿病组各项指标标化前后与对照组之间的差异均有显著性（P均＜0．01）；标化前后各项指标在空腹血糖受损组及糖尿病组之间的差异亦有显著性（P均＜0．01）。结论：随着血糖的升高，左心构型标化前指标（ LVPWT、LVM、LAA、LVV）除LVEDd外及标化后指标（ LVEDdi、LVPWTi、LVMi、LAAi、LVVi）逐渐增大；标化后指标可以更敏感地反映糖尿病患者左心构型的改变。
目的：通過體錶麵積對左心構型超聲指標進行標化，觀察標化前、後各項指標在空腹血糖受損組及糖尿病組的變化；併將標化前後指標對比分析，初步探討標化前、後指標反映左心構型變化的敏感性。方法：于我院2012年1月～2013年12月門診及住院糖尿病病人中選擇80例患者，按1999年WHO規定的糖尿病的診斷標準分成兩組：空腹血糖受損組及糖尿病組。于我院健康體檢中心選擇20例研究對象為正常對照組。心電觸髮二維切麵超聲于心髒舒張期末測量超聲參數，將這些參數用體錶麵積標化，一方麵觀察標化前後各項指標隨血糖升高髮生的變化，另一方麵將標化前後指標對比，通過統計學處理分析，觀察標化前後指標在反映血糖升高對左心構型的改變方麵的敏感性和穩定性。結果：上述標化前後各項指標均值在空腹血糖受損組及糖尿病組逐漸增大，其中標化前空腹血糖受損組各項指標與正常對照組之間的差異無顯著性（P＞0．05），標化後與正常對照組之間的差異有顯著性（P均＜0．01）；糖尿病組各項指標標化前後與對照組之間的差異均有顯著性（P均＜0．01）；標化前後各項指標在空腹血糖受損組及糖尿病組之間的差異亦有顯著性（P均＜0．01）。結論：隨著血糖的升高，左心構型標化前指標（ LVPWT、LVM、LAA、LVV）除LVEDd外及標化後指標（ LVEDdi、LVPWTi、LVMi、LAAi、LVVi）逐漸增大；標化後指標可以更敏感地反映糖尿病患者左心構型的改變。
목적：통과체표면적대좌심구형초성지표진행표화，관찰표화전、후각항지표재공복혈당수손조급당뇨병조적변화；병장표화전후지표대비분석，초보탐토표화전、후지표반영좌심구형변화적민감성。방법：우아원2012년1월～2013년12월문진급주원당뇨병병인중선택80례환자，안1999년WHO규정적당뇨병적진단표준분성량조：공복혈당수손조급당뇨병조。우아원건강체검중심선택20례연구대상위정상대조조。심전촉발이유절면초성우심장서장기말측량초성삼수，장저사삼수용체표면적표화，일방면관찰표화전후각항지표수혈당승고발생적변화，령일방면장표화전후지표대비，통과통계학처리분석，관찰표화전후지표재반영혈당승고대좌심구형적개변방면적민감성화은정성。결과：상술표화전후각항지표균치재공복혈당수손조급당뇨병조축점증대，기중표화전공복혈당수손조각항지표여정상대조조지간적차이무현저성（P＞0．05），표화후여정상대조조지간적차이유현저성（P균＜0．01）；당뇨병조각항지표표화전후여대조조지간적차이균유현저성（P균＜0．01）；표화전후각항지표재공복혈당수손조급당뇨병조지간적차이역유현저성（P균＜0．01）。결론：수착혈당적승고，좌심구형표화전지표（ LVPWT、LVM、LAA、LVV）제LVEDd외급표화후지표（ LVEDdi、LVPWTi、LVMi、LAAi、LVVi）축점증대；표화후지표가이경민감지반영당뇨병환자좌심구형적개변。
Objective:To preliminarily evaluate the sensitivity of the indicators before and after quantitative standardization to the variation of the cardiac configuration in patients with diabetes mellitus.Methods:Eighty clinical patients or inpatients with diabetes mellitus(DM) were included through January 2012 to December 2013,and allocated to group of impaired fasting glucose and diabetics in compliance with the 1999 WHO criteria for DM,and another 20 healthy subjects from our physical examination center were volunteer as normal controls .Electrocardiography( ECG)-gated two-dimensional data at the end-diastolic phase were acquired to measure the ultrasound parameters that were used to standardize the body surface area .Each indicator was observed con-cerning the changes to the elevated glucose level in relation with the cardiac geometry ,and statistically evaluated before and after standardization .Results:No statistical difference was found in parameters before standardization between the control group IFG group (P>0.05),yet the indicators after standardi-zation were obviously different between the controls and IFG group(P <0.01).The indicators before and after standardization were totally different be-tween the controls and patients with diabetes mellitus ,as well as IFG patients and diabetics .The variation coefficient for the indicators after standardization was less than that before standardization .Conclusion:All indicators before and after standardization of left ventricular geometry tend to increase with eleva-tion of the blood sugar except LVEDd,suggesting that these indicators after standardization may sensitively reveal the changes of cardiac geometry in pa-tients with diabetes mellitus.
