CAJ | 학술논문

目的：探讨针灸治疗失眠患者临床疗效观察及对炎症因子水平的影响。方法：119例患者按照随机数字表法随机分为对照组（n＝57）和治疗组（n＝62）。对照组采用常规治疗方法，治疗组采用针灸治疗。两组患者均以10d为1疗程，连续治疗3个疗程。评价两组治疗疗效、治疗前后睡眠质量和炎症因子水平变化以及治疗期间不良反应发生情况。结果：治疗组治疗3个疗程后总有效率（88．71％）显著高于对照组（73．68％），且具有统计学差异（ P＜0．05）；两组睡眠质量、睡眠时间、睡眠障碍、入睡时间、日间功能障碍、睡眠效率及PS Q I量表总分治疗后较治疗前显著降低，且具有统计学差异（ P＜0．05）；治疗组睡眠质量、睡眠时间、睡眠障碍、入睡时间、日间功能障碍、睡眠效率及PS Q I量表总分治疗后显著低于对照组，且具有统计学差异（P＜0．05）；治疗组 TNF‐α、IL‐6水平见治疗前显著降低，且具有统计学差异（P＜0．05）；两组间比较不具有统计学差异（P＞0．05）；两组均未见明显不良反应。结论：针灸治疗失眠患者临床疗效显著，可明显降低T N F‐α、IL‐6水平，从而延长睡眠时间。
목적：탐토침구치료실면환자림상료효관찰급대염증인자수평적영향。방법：119례환자안조수궤수자표법수궤분위대조조（n＝57）화치료조（n＝62）。대조조채용상규치료방법，치료조채용침구치료。량조환자균이10d위1료정，련속치료3개료정。평개량조치료료효、치료전후수면질량화염증인자수평변화이급치료기간불량반응발생정황。결과：치료조치료3개료정후총유효솔（88．71％）현저고우대조조（73．68％），차구유통계학차이（ P＜0．05）；량조수면질량、수면시간、수면장애、입수시간、일간공능장애、수면효솔급PS Q I량표총분치료후교치료전현저강저，차구유통계학차이（ P＜0．05）；치료조수면질량、수면시간、수면장애、입수시간、일간공능장애、수면효솔급PS Q I량표총분치료후현저저우대조조，차구유통계학차이（P＜0．05）；치료조 TNF‐α、IL‐6수평견치료전현저강저，차구유통계학차이（P＜0．05）；량조간비교불구유통계학차이（P＞0．05）；량조균미견명현불량반응。결론：침구치료실면환자림상료효현저，가명현강저T N F‐α、IL‐6수평，종이연장수면시간。
Objective :To investigate the clinical efficacy of acupuncture treatment in patients with insomnia and its impact on levels of inflammatory cytokines .Methods :119 cases of patients according to the random number table , randomly divided into a control group (n=57) and treatment group (n=62) .Control group with conventional therapy , the treatment group received acupuncture treatment .Two groups of patients were 10d for a course of treatment ,continu‐ous treatment of three courses .Evaluation of the efficacy of treatment in both groups before and after treatment and poor sleep quality and levels of inflammatory cytokines during treatment response were observed .Results :The treatment group after three courses of treatment efficiency (88 .71% ) was significantly higher (73 .68% ) ,and had a statistically significant difference (P<0 .05);two sleep quality ,sleep duration ,sleep disorders ,sleep time daytime dysfunction ,sleep efficiency and after treatment PSQI total score was significantly lower than before treatment ,and had a statistically significant difference (P<0 .05);treatment group ,sleep quality ,sleep duration ,sleep disorders ,sleep time and daytime function disorders ,sleep efficiency and PSQI total score after treatment was significantly lower than the control group ,and had a significant difference (P<0 .05);Treatment group TNF‐α,IL‐6 levels before treatment to see a significant reduction ,and had a statistically significant difference (P<0 .05);between the two groups was not statistically different (P>0 .05);the two groups showed no significant adverse reactions .Conclusion :Acupuncture treatment of insomnia in patients with clini‐cally significant effect ,can significantly reduce TNF‐α,IL‐6 levels ,thus prolonging the sleep time .