CAJ | 학술논문

目的探讨老年溃疡性结肠炎(UC)患者的生活质量及其影响因素. 方法应用中文版炎症性肠病问卷(C-IBDQ),对老年UC患者进行横断面调查,评价其生活质量(QOL);通过相关分析和多元线性回归分析,筛选出影响老年UC患者QOL的主要因素. 结果 90例老年UC患者完成问卷,QOL总分为(175.7±37.6)分,各维度评分均有下降,以经济负担、全身症状及情感功能下降较为明显;多元线性回归分析提示,对老年UC患者QOL有影响的因素为性别、病情、病程、疾病活动度及付费方式等;男性UC患者肠道症状得分明显高于女性患者[(53.9±12.1)分比(49.1±10.5)分,P=0.049];病程＜1年的患者的QOL明显低于病程1年以上者(P＜0.05);重型UC患者的QOL明显低于轻型患者(P＜0.05);活动期患者QOL明显低于缓解期患者(149.7±35.1比193.9±27.3;t=6.731,P=0.000);医疗费用主要由个人负担的患者QOL较费用大部分由医保支付的患者低,二者在全身症状、社会功能及经济负担等3个维度差异有统计学意义(P＜0.05). 结论老年UC患者QOL均有不同程度受损;影响老年UC患者QOL的因素有性别、病情、病程、疾病活动度及付费方式;经济负担对UC患者QOL有明显影响.
목적 탐토노년궤양성결장염(UC)환자적생활질량급기영향인소. 방법 응용중문판염증성장병문권(C-IBDQ),대노년UC환자진행횡단면조사,평개기생활질량(QOL);통과상관분석화다원선성회귀분석,사선출영향노년UC환자QOL적주요인소. 결과 90례노년UC환자완성문권,QOL총분위(175.7±37.6)분,각유도평분균유하강,이경제부담、전신증상급정감공능하강교위명현;다원선성회귀분석제시,대노년UC환자QOL유영향적인소위성별、병정、병정、질병활동도급부비방식등;남성UC환자장도증상득분명현고우녀성환자[(53.9±12.1)분비(49.1±10.5)분,P=0.049];병정＜1년적환자적QOL명현저우병정1년이상자(P＜0.05);중형UC환자적QOL명현저우경형환자(P＜0.05);활동기환자QOL명현저우완해기환자(149.7±35.1비193.9±27.3;t=6.731,P=0.000);의료비용주요유개인부담적환자QOL교비용대부분유의보지부적환자저,이자재전신증상、사회공능급경제부담등3개유도차이유통계학의의(P＜0.05). 결론 노년UC환자QOL균유불동정도수손;영향노년UC환자QOL적인소유성별、병정、병정、질병활동도급부비방식;경제부담대UC환자QOL유명현영향.
Objective To investigate the quality of life (QOL) and its influential factors in the aged patients with ulcerative colitis (UC).Methods A cross-sectional survey of the UC patients was conducted by Chinese version of inflammatory bowel disease questionnaire (C-IBDQ).The influential factors for QOL in elderly patients with UC were evaluated and analyzed by correlation analysis and multiple linear regression analysis.Results A total of 90 aged UC patients finished the questionnaire study.The overall score of QOL in the aged UC patients was (175.7±37.6),and the score of each item was decreased,especially in the aspect of economic burden,emotional function and systemic symptoms.Multiple linear regression analysis indicated that the influential factors for QOL were sex,disease severity,duration,disease activity and the payment.The scores of bowel symptoms were higher in men than in women [(53.9±12.1) vs.(49.1±10.5),P=0.049].The QOL scores were lower in patients with the duration less than one year than over one year (P＜ 0.05).The QOL scores were lower in severe patients than in mild patients (P＜ 0.05).The QOL scores were lower in patients during active period than during remission period [(149.7 ± 35.1) vs.(193.9 ± 27.3),t=6.731,P=0.000].The QOL scores of patients whose medical cost was mainly paid by themselves were lower than those paid by insurance.And there were significant differences in systemic symptom,social function and economic burden (all P＜ 0.05).Conclusions The QOL of the aged UC patients is impaired in varying degree.The influential factors for QOL are sex,disease severity,duration,disease activity and the payment.The QOL in UC patients is obviously affected by economic burden.