中国药师
中國藥師
중국약사
China Pharmacist
2015年
10期
1792-1795
,共4页
李晰%张琰%吴丹%赵玫%窦晓飞%刘梅
李晰%張琰%吳丹%趙玫%竇曉飛%劉梅
리석%장염%오단%조매%두효비%류매
肠肽胶囊%质量标准%薄层色谱法%高效液相色谱法
腸肽膠囊%質量標準%薄層色譜法%高效液相色譜法
장태효낭%질량표준%박층색보법%고효액상색보법
Changtai capsules%Quality standard%TLC%HPLC
目的:本研究旨在建立肠肽胶囊的质量标准. 方法:采用薄层色谱法鉴别薏苡仁、蒲公英、白芷、厚朴,采用HPLC法测定三七中有效成分三七皂苷R1、人参皂苷Rg1 和人参皂苷Rb1 的含量. 结果: 薄层鉴别斑点清晰,阴性对照无干扰;三七中有效成分三七皂苷R1、人参皂苷Rg1 和人参皂苷Rb1 分别在40 ~ 300 μg·ml-1、320 ~ 2 400 μg·ml-1、80 ~ 600 μg· ml-1范围内线性关系良好;平均加样回收率分别为99. 76%、99. 33%、99. 48%, RSD分别为0. 42%、0. 48%、0. 63%(n=9).结论:该方法可用于肠肽胶囊的质量控制.
目的:本研究旨在建立腸肽膠囊的質量標準. 方法:採用薄層色譜法鑒彆薏苡仁、蒲公英、白芷、厚樸,採用HPLC法測定三七中有效成分三七皂苷R1、人參皂苷Rg1 和人參皂苷Rb1 的含量. 結果: 薄層鑒彆斑點清晰,陰性對照無榦擾;三七中有效成分三七皂苷R1、人參皂苷Rg1 和人參皂苷Rb1 分彆在40 ~ 300 μg·ml-1、320 ~ 2 400 μg·ml-1、80 ~ 600 μg· ml-1範圍內線性關繫良好;平均加樣迴收率分彆為99. 76%、99. 33%、99. 48%, RSD分彆為0. 42%、0. 48%、0. 63%(n=9).結論:該方法可用于腸肽膠囊的質量控製.
목적:본연구지재건립장태효낭적질량표준. 방법:채용박층색보법감별의이인、포공영、백지、후박,채용HPLC법측정삼칠중유효성분삼칠조감R1、인삼조감Rg1 화인삼조감Rb1 적함량. 결과: 박층감별반점청석,음성대조무간우;삼칠중유효성분삼칠조감R1、인삼조감Rg1 화인삼조감Rb1 분별재40 ~ 300 μg·ml-1、320 ~ 2 400 μg·ml-1、80 ~ 600 μg· ml-1범위내선성관계량호;평균가양회수솔분별위99. 76%、99. 33%、99. 48%, RSD분별위0. 42%、0. 48%、0. 63%(n=9).결론:해방법가용우장태효낭적질량공제.
Objective:To establish the quality standard for Changtai capsules. Methods:The components including coicis semen, taraxaci herba, angelicae dahuricae radix and magnoliae officinalis cortex were identified by TLC. The content of notoginsenoside R1 , ginsenoside Rg1 and ginsenoside Rb1 in notoginseng radix et ehizoma was detected by HPLC. Results:The characteristic spots in TLC were clear without any interference. The linear range of notoginsenoside R1, ginsenoside Rg1 and ginsenoside Rb1 was 40-300 μg· ml-1 , 320-2 400μg·ml-1 and 80-600μg·ml-1 , respectively. The average recovery was 99. 76%, 99. 33% and 99. 48% with RSD of 0. 42%, 0. 48% and 0. 63% (n=9), respectively. Conclusion:The methods used for the identification and quantification are sen-sitive, simple and accurate, which can be used for the quality control of Changtai capsules.
