CAJ | 학술논문

目的:研究和提高双柏祛瘀散的质量标准. 方法: 采用显微鉴别法对关黄柏、大黄、侧柏叶、穿心莲进行了显微鉴别;采用薄层色谱法对关黄柏、穿心莲、大黄进行TLC鉴别;采用HPLC法对双柏祛瘀散中关黄柏的有效成分盐酸小檗碱进行含量测定,并确定含量下限. 结果:显微鉴别方法简捷;薄层鉴别斑点清晰,且阴性对照无干扰;盐酸小檗碱含量在0. 010~0. 400 μg范围内呈良好的线性关系(r=0. 999 9),加样回收率为99. 51%,RSD为0. 31%(n=6). 结论: 该法能有效地控制双柏祛瘀散的药品质量,有利于医院制剂标准质量的提升.
목적:연구화제고쌍백거어산적질량표준. 방법: 채용현미감별법대관황백、대황、측백협、천심련진행료현미감별;채용박층색보법대관황백、천심련、대황진행TLC감별;채용HPLC법대쌍백거어산중관황백적유효성분염산소벽감진행함량측정,병학정함량하한. 결과:현미감별방법간첩;박층감별반점청석,차음성대조무간우;염산소벽감함량재0. 010~0. 400 μg범위내정량호적선성관계(r=0. 999 9),가양회수솔위99. 51%,RSD위0. 31%(n=6). 결론: 해법능유효지공제쌍백거어산적약품질량,유리우의원제제표준질량적제승.
Objective:To study and promote the quality standard for Shuangbai Quyu powder. Methods:A microscopic identifi-cation method was performed to identify Phellodendri amurensis cortex, Rhei radix et rhizoma, Platycladi cacumen and Andrographis herba. TLC was performed to identify Phellodendri amurensis cortex, Andrographis herba and Rhei radix et rhizoma. HPLC was used to determine the content of berberine hydrochloride in Phellodendri amurensis cortex. and the lower limit was determined. Results: The microscopic identification method was simple. The spots in TLC were distinct without any interference from the negative coutrol. Ber-berine hydrochloride had a good linear range of 0. 010-0. 400 μg(r=0. 999 9). The average recovery was 99. 51%, and RSD was 0. 31% (n=6). Conclusion:The method can be used for the quality control of Shuangbai Quyu powder effectively,which is beneficial to the quality standard promotion of hospital preparations.