CAJ | 학술논문

目的:探讨辛伐他汀联合丹参酮对急性脑梗死患者的治疗效果. 方法:急性脑梗死患者随机分为观察组( n=50 )与对照组(n=50). 对照组给予丹参酮治疗,观察组在对照组基础上加用辛伐他汀治疗,疗程均为14 d. 治疗前后对两组患者的NIHSS(神经功能缺损程度)、ADL(日常生活活动量)及治疗疗效进行综合评价并比较. 结果: 与治疗前比较,两组患者NIHSS与ADL评分均明显改善,且观察组改善程度明显优于对照组(P<0. 05);观察组治疗总有效率为90%,明显高于对照组的70%(P<0. 05). 结论:辛伐他汀联合丹参酮治疗急性脑梗死疗效显著,且能明显改善患者神经缺损及日常生活活动量.
목적:탐토신벌타정연합단삼동대급성뇌경사환자적치료효과. 방법:급성뇌경사환자수궤분위관찰조( n=50 )여대조조(n=50). 대조조급여단삼동치료,관찰조재대조조기출상가용신벌타정치료,료정균위14 d. 치료전후대량조환자적NIHSS(신경공능결손정도)、ADL(일상생활활동량)급치료료효진행종합평개병비교. 결과: 여치료전비교,량조환자NIHSS여ADL평분균명현개선,차관찰조개선정도명현우우대조조(P<0. 05);관찰조치료총유효솔위90%,명현고우대조조적70%(P<0. 05). 결론:신벌타정연합단삼동치료급성뇌경사료효현저,차능명현개선환자신경결손급일상생활활동량.
Objective:To analyze the effect of simvastatin combined with tanshinone in the treatment of patients with acute cere-bral infarction. Methods:The patients with acute cerebral infarction were randomly divided into the treatment group (n=50) and the control group (n=50). The control group was given tanshinone treatment, the treatment group was given simvastatin treatment addi-tionally, and the treatment course was 14 d. The NIHSS ( nerve function defect degree) , ADL ( daily life activity) and the treatment effect before and after the treatment were comprehensively evaluated and compared between the two groups. Results: Compared with those before the treatment, the NIHSS and ADL scores were significantly improved in the two groups after the treatment, and the differ-ences were statistically significant (P<0. 05), and the improvement in the treatment group was significantly better than that in the control group with statistical significance (P<0. 05). The total effective rate of the observation group was 98%, which was higher than that (70%) in the control group (P<0. 05). Conclusion: Simvastatin combined with tanshinone in the treatment of acute cerebral infarction shows obvious therapeutic effect, which can obviously improve neurologic deficits and daily life activity, and is worthy of fur-ther clinical application.