CAJ | 학술논문

目的应用血管回声跟踪技术(ET)对正常高值血压合并吸烟者颈动脉弹性进行检测,探讨吸烟对正常高值血压者颈动脉弹性的影响.方法应用ET检测92例正常高值血压合并吸烟者与37例正常对照组双侧颈动脉的弹性参数,即硬度指数(β)、压力-应变弹性系数(Ep)、顺应性(AC)、脉搏波速度(PWVβ),进行对比分析,并用二维超声测量颈动脉内中膜厚度(IMT),采用偏相关分析对吸烟相关影响因素与颈动脉弹性间的相关性进行分析.结果 2组间颈动脉IMT比较,差异无统计学意义(P>0.05),但正常高值合并吸烟组的β、Ep、PWVβ值均高于正常对照组,AC值低于正常对照组,差异均有统计学意义(P<0.05);偏相关分析结果显示平均每日吸烟支数、吸烟年数均与β、Ep、PWVβ呈显著正相关,与AC呈显著负相关;吸烟年数与颈动脉IMT呈显著正相关.结论吸烟可加重正常高值血压者的颈动脉弹性功能降低,ET技术能早期诊断动脉弹性病变.
목적 응용혈관회성근종기술(ET)대정상고치혈압합병흡연자경동맥탄성진행검측,탐토흡연대정상고치혈압자경동맥탄성적영향.방법 응용ET검측92례정상고치혈압합병흡연자여37례정상대조조쌍측경동맥적탄성삼수,즉경도지수(β)、압력-응변탄성계수(Ep)、순응성(AC)、맥박파속도(PWVβ),진행대비분석,병용이유초성측량경동맥내중막후도(IMT),채용편상관분석대흡연상관영향인소여경동맥탄성간적상관성진행분석.결과 2조간경동맥IMT비교,차이무통계학의의(P>0.05),단정상고치합병흡연조적β、Ep、PWVβ치균고우정상대조조,AC치저우정상대조조,차이균유통계학의의(P<0.05);편상관분석결과현시평균매일흡연지수、흡연년수균여β、Ep、PWVβ정현저정상관,여AC정현저부상관;흡연년수여경동맥IMT정현저정상관.결론 흡연가가중정상고치혈압자적경동맥탄성공능강저,ET기술능조기진단동맥탄성병변.
Objective To investigate the effect of smoking on carotid elasticity in smokers with high?normal blood pressure by echo tracking tech?nique(ET). Methods ET was adopted to test 92 smokers with high?normal blood pressure and 37 normal controls for elastic parameters of bilater?al carotid arteries,i.e.,stiffness index(β),pressure?strian elastic coefficient(Ep),compliance(AC),and pulse wave velocity(PWVβ). The test results were compared and analyzed. Besides,the two?dimensional ultrasound was used to measure intima?media thickness(IMT)of carotid arter?ies. The partial correlation analysis was conducted to analyze the correlation of the factors related to smoking with arterial elastic parameters. Results There was no statistically significant difference in IMT between the two groups(P>0.05). Compared with the normal controlled group,β,Ep,and PWVβwere conspicuously higher and AC was significantly lower in smokers with high?normal blood pressure,with statistical significance(P<0.05). The partial correlation analysis showed that the average number of cigarettes smoked per day and the years of smoking were positively correlat?ed withβ,Ep,and PWVβand negatively with AC. There was positive correlation of the years of smoking and carotid IMT. Conclusion Smoking aggravates elasticity function reduction of carotid arteries in people with high?normal blood pressure. ET can early diagnose arterial elastic lesions.