中国医药
中國醫藥
중국의약
China Medicine
2015年
10期
1509-1511
,共3页
妊娠%房间隔缺损%新生儿
妊娠%房間隔缺損%新生兒
임신%방간격결손%신생인
Pregnancy%Atrial septal defects%Neonatal
目的 分析房间隔缺损(ASD)产妇所生产新生儿临床资料,探讨产妇ASD对新生儿的影响.方法 回顾性分析2003年1月至2013年10月首都医科大学附属北京安贞医院收治的83例ASD产妇所生产83名新生儿(观察组)的临床资料,另选取同期健康产妇所生产新生儿136名为对照组.比较2组新生儿出生体质量和身长及早产儿、小于胎龄儿和窒息发生率.结果 观察组新生儿出生体质量和身长均明显低于对照组[(2 946±547)g比(3 187 ±420)g、(48.9 ±2.3)cm比(50.4±1.7)cm],早产儿和小于胎龄儿发生率高于对照组[19.3％(16/83)比8.1％ (11/136),8.4％ (7/83)比0.7％ (1/136)],差异有统计学意义(P＜0.05),窒息发生率与对照组比较差异无统计学意义[6.0％(5/83)比1.5％ (2/136)] (P＞0.05).观察组中合并肺动脉高压产妇37例,其新生儿出生体质量为(2 727±616)g,身长为(47.9±3.0)cm,早产儿和小于胎龄儿发生率分别为35.1％ (13/37)和10.8％ (4/37),与对照组比较差异有统计学意义(P＜0.05或P＜0.01),新生儿窒息发生率为10.8％ (4/37),与对照组比较差异无统计学意义(P＞0.05).观察组早产儿、小于胎龄儿和窒息发生率在美国纽约心脏病协会心功能分级Ⅰ级产妇中分别为6.7％(2/30)、13.3％(4/30)和3.3％ (1/30),Ⅱ级产妇中分别为19.0％(8/42)、2.4％ (1/42)和2.4％(1/42),Ⅲ～Ⅳ级产妇中分别为54.5％(6/11)、18.2％(2/11)和27.3％(3/11).结论 ASD产妇,尤其是合并肺动脉高压产妇所生产新生儿出生体质量和身长低于正常孕妇新生儿,早产儿、小于胎龄儿发生率高于正常孕妇新生儿;心功能Ⅲ～Ⅳ级孕妇早产儿和新生儿窒息发生率高.
目的 分析房間隔缺損(ASD)產婦所生產新生兒臨床資料,探討產婦ASD對新生兒的影響.方法 迴顧性分析2003年1月至2013年10月首都醫科大學附屬北京安貞醫院收治的83例ASD產婦所生產83名新生兒(觀察組)的臨床資料,另選取同期健康產婦所生產新生兒136名為對照組.比較2組新生兒齣生體質量和身長及早產兒、小于胎齡兒和窒息髮生率.結果 觀察組新生兒齣生體質量和身長均明顯低于對照組[(2 946±547)g比(3 187 ±420)g、(48.9 ±2.3)cm比(50.4±1.7)cm],早產兒和小于胎齡兒髮生率高于對照組[19.3％(16/83)比8.1％ (11/136),8.4％ (7/83)比0.7％ (1/136)],差異有統計學意義(P＜0.05),窒息髮生率與對照組比較差異無統計學意義[6.0％(5/83)比1.5％ (2/136)] (P＞0.05).觀察組中閤併肺動脈高壓產婦37例,其新生兒齣生體質量為(2 727±616)g,身長為(47.9±3.0)cm,早產兒和小于胎齡兒髮生率分彆為35.1％ (13/37)和10.8％ (4/37),與對照組比較差異有統計學意義(P＜0.05或P＜0.01),新生兒窒息髮生率為10.8％ (4/37),與對照組比較差異無統計學意義(P＞0.05).觀察組早產兒、小于胎齡兒和窒息髮生率在美國紐約心髒病協會心功能分級Ⅰ級產婦中分彆為6.7％(2/30)、13.3％(4/30)和3.3％ (1/30),Ⅱ級產婦中分彆為19.0％(8/42)、2.4％ (1/42)和2.4％(1/42),Ⅲ～Ⅳ級產婦中分彆為54.5％(6/11)、18.2％(2/11)和27.3％(3/11).結論 ASD產婦,尤其是閤併肺動脈高壓產婦所生產新生兒齣生體質量和身長低于正常孕婦新生兒,早產兒、小于胎齡兒髮生率高于正常孕婦新生兒;心功能Ⅲ～Ⅳ級孕婦早產兒和新生兒窒息髮生率高.
목적 분석방간격결손(ASD)산부소생산신생인림상자료,탐토산부ASD대신생인적영향.방법 회고성분석2003년1월지2013년10월수도의과대학부속북경안정의원수치적83례ASD산부소생산83명신생인(관찰조)적림상자료,령선취동기건강산부소생산신생인136명위대조조.비교2조신생인출생체질량화신장급조산인、소우태령인화질식발생솔.결과 관찰조신생인출생체질량화신장균명현저우대조조[(2 946±547)g비(3 187 ±420)g、(48.9 ±2.3)cm비(50.4±1.7)cm],조산인화소우태령인발생솔고우대조조[19.3％(16/83)비8.1％ (11/136),8.4％ (7/83)비0.7％ (1/136)],차이유통계학의의(P＜0.05),질식발생솔여대조조비교차이무통계학의의[6.0％(5/83)비1.5％ (2/136)] (P＞0.05).관찰조중합병폐동맥고압산부37례,기신생인출생체질량위(2 727±616)g,신장위(47.9±3.0)cm,조산인화소우태령인발생솔분별위35.1％ (13/37)화10.8％ (4/37),여대조조비교차이유통계학의의(P＜0.05혹P＜0.01),신생인질식발생솔위10.8％ (4/37),여대조조비교차이무통계학의의(P＞0.05).관찰조조산인、소우태령인화질식발생솔재미국뉴약심장병협회심공능분급Ⅰ급산부중분별위6.7％(2/30)、13.3％(4/30)화3.3％ (1/30),Ⅱ급산부중분별위19.0％(8/42)、2.4％ (1/42)화2.4％(1/42),Ⅲ～Ⅳ급산부중분별위54.5％(6/11)、18.2％(2/11)화27.3％(3/11).결론 ASD산부,우기시합병폐동맥고압산부소생산신생인출생체질량화신장저우정상잉부신생인,조산인、소우태령인발생솔고우정상잉부신생인;심공능Ⅲ～Ⅳ급잉부조산인화신생인질식발생솔고.
Objective To analyze the clinical data of neonatus of puerperal with atrial septal defects (ASD) and to explore the influence of maternal ASD on the neonatus.Method Clinical data of 83 neonates of 83 puerperas with ASD (obserwation group) and 136 neonates of healthy puerperas (control group) from January 2003 to October 2013 was retrospectively analyzed.The birth weight,birth height,incidences of premature birth,small for gestational age and neonatal asphyxia were compared between the two groups.Result In observation group,the birth weight and birth height were significantly less,the incidences of premature birth and small for gestational age were significantly higher compared with those in control group [(2 946 ± 547) g vs (3 187 ± 420) g,(48.9±2.3) cmvs (50.4±1.7) cm,19.3％ (16/83) vs8.1％ (11/136),8.4％ (7/83) vs0.7％ (1/136)] (P ＜ 0.05),while no significantly difference was found regarding incidence of neonatal asphyxia [6.0％ (5/83) vs 1.5％ (2/136)] (P ＞0.05).In observation group,37 puerperas were complicated with pulmonary arterial hypertension and their neonates had less birth weight [(2 727 ± 616)g] and birth height [(47.9 ± 3.0)cm],higher incidences of premature birth [35.1％ (13/37)] and small for gestational age [10.8％ (4/37)],similar incidence of neonatal asphyxia [10.8％ (4/37)] compared with those in control group.The incidences of premature birth,small for gestational and neonatal asphyxia were 6.7％ (2/30),13.3％ (4/30) and 3.3％ (1/30) in puerperas of New York heart association (NYHA) class Ⅰ,19.0％ (8/42),2.4％ (1/42) and 2.4％ (1/42) in puerperas of NYHA class Ⅱ,54.5％ (6/11),18.2％ (2/11) and 27.3％ (3/11) in puerperas of NYHA class Ⅲ-Ⅳ.Conclusions The neonates of puerperas with ASD,especially those complicated with pulmonary arterial hypertension,have less birth weight and birth height,higher incidences of premature birth and small for gestational age compared with common neonates;the incidence of premature birth and neonatal asphyxia are higher for pregnant women of NYHA class Ⅲ-Ⅳ.
