CAJ | 학술논문

目的探讨H型高血压与不稳定型心绞痛患者冠脉病变程度的相关性. 方法收集2011年10月至20 12年10月于齐齐哈尔医学院附属第三医院心内科入院的原发性高血压病合并不稳定型心绞痛的患者294例. 其中同型半胱氨酸( Hcy)水平≥10μmol/L为研究组,Hcy<10μmol/L为对照组. 所有患者行冠状动脉造影检查,采用酶法测定血清Hcy水平,采用Gensini冠脉评分系统对冠脉严重程度进行评价. 比较Hcy水平的差异与冠脉病变严重程度的关系. 结果研究组中Gensini积分明显高于对照组,差异有统计学意义(P<0.05). 结论 H型高血压和血清高Hcy水平均为冠心病的危险因素,两者与冠脉病变的严重程度有关.
목적 탐토H형고혈압여불은정형심교통환자관맥병변정도적상관성. 방법 수집2011년10월지20 12년10월우제제합이의학원부속제삼의원심내과입원적원발성고혈압병합병불은정형심교통적환자294례. 기중동형반광안산( Hcy)수평≥10μmol/L위연구조,Hcy<10μmol/L위대조조. 소유환자행관상동맥조영검사,채용매법측정혈청Hcy수평,채용Gensini관맥평분계통대관맥엄중정도진행평개. 비교Hcy수평적차이여관맥병변엄중정도적관계. 결과 연구조중Gensini적분명현고우대조조,차이유통계학의의(P<0.05). 결론 H형고혈압화혈청고Hcy수평균위관심병적위험인소,량자여관맥병변적엄중정도유관.
Objective To investigate the association between H type hypertension and the degree of coronary artery lesions in patients with unstable angina .Methods We selected 294 inpatient suffered primary hypertension and coronary heart disease in the cardiology department of the third affiliated hospital of Qiqihar Medical College between October 2011 and October 2012.They were divided into H group (homocysteine (Hcy) level more than 10μmol/L,n=144) and control group (Hcy level less than 10μmol/L,n=150).All the patients underwent coronary angiography .The Hcy levels were determined using immune -assay and compared .The Gensini grading system was employed to evaluate the severity of coronary arteries .Investigate the correlation between the differences of Hcy levels and the severity of coronary artery lesions .Results Gensini score in research group was significantly higher than the control group , the difference was statistically significant ( P<0. 05).Conclusions H type hypertension and serum Hcy levels may be a risk factor for coronary heart disease (CHD), both two factors may lead to cardiovascular events .