CAJ | 학술논문

目的：探讨Ⅰ型M adelung综合征的临床特征及C T、M RI影像特点，提高对本病的认识。方法收集经临床证实的Ⅰ型M adelung综合征15例，回顾性分析其临床资料及C T、M RI影像表现，C T平扫5例，M RI平扫10例。结果15例中女性6例，男性9例。男性均有酗酒史，伴酒精性肝硬化，女性有代谢障碍性疾病，其中糖尿病2例，高血压2例，甲状腺功能减退症1例，高尿酸血症1例。临床上均表现为颈部对称性增粗，女性主要位于双侧后项部，男性主要位于双侧颈部、项部、肩背部及上胸部。CT均显示皮下及肌间隙内均一脂肪密度，呈弥漫性、对称性分布，边界不清，无包膜，无肿块，无钙化，内可见索条状纤维分隔，邻近肌肉受压、移位、萎缩、变细。M RI显示病变区均表现为短 T1长 T2信号，压脂序列均呈低信号。结论Ⅰ型M adelung综合征为男性发病，女性发病罕见，脂肪组织的异常沉积存在性别差异，女性患者病变范围比较局限，主要累及后颈部，而男性患者范围广泛，主要累及颈部、项部、肩背部及上胸部。
목적：탐토Ⅰ형M adelung종합정적림상특정급C T、M RI영상특점，제고대본병적인식。방법수집경림상증실적Ⅰ형M adelung종합정15례，회고성분석기림상자료급C T、M RI영상표현，C T평소5례，M RI평소10례。결과15례중녀성6례，남성9례。남성균유후주사，반주정성간경화，녀성유대사장애성질병，기중당뇨병2례，고혈압2례，갑상선공능감퇴증1례，고뇨산혈증1례。림상상균표현위경부대칭성증조，녀성주요위우쌍측후항부，남성주요위우쌍측경부、항부、견배부급상흉부。CT균현시피하급기간극내균일지방밀도，정미만성、대칭성분포，변계불청，무포막，무종괴，무개화，내가견색조상섬유분격，린근기육수압、이위、위축、변세。M RI현시병변구균표현위단 T1장 T2신호，압지서렬균정저신호。결론Ⅰ형M adelung종합정위남성발병，녀성발병한견，지방조직적이상침적존재성별차이，녀성환자병변범위비교국한，주요루급후경부，이남성환자범위엄범，주요루급경부、항부、견배부급상흉부。
Objective To investigate the clinical characteristics and CT ,MRI features of Type Ⅰ Madelung syndrome , and to increase awareness of the disease .Methods Fifteen cases of TypeⅠ Madelung syndrome proved by surgery and pa‐thology were collected .The CT and MRI features of TypeⅠ Madelung syndrome in 15 patients were reviewed retrospec‐tively ,including 5 cases scaned by unenhanced CT and 10 cases scaned by unenhanced MRI .Results There existed 6 fe‐male cases and 9 male cases among these 15 patients .All male cases had alcoholism history ,along with alcoholic cirrhosis . Female cases had metabolic disorders ,including 2 cases of diabetes and hypertension respectively ,one case of hypothyroid‐ism and hyperuricemia respectively .15 patients of type I M adelung syndrome all manifested thickened neck symmetrically . The lesions of females were mainly located in the bilateral neck ,while lesions of males mainly located in bilateral neck , napex ,shoulder and back ,and upper chest .CT scans all showed uniform fat density in subcutis and muscle compartment , located pervasively and symmetrically ,without envelope ,lumps or calcification .Strip cable fiber separations can be seen in the involvement .What’s more ,the muscles around were compressed ,translocated ,atrophic and thin .All lesions were displayed hypointensity on T1 WI and hyperintensity on T2 WI ,hypointensity on fat‐suppression sequence .Conclusion Type Ⅰ Madelung syndrome is frequently seen in males ,rarely seen in women .Abnormal accumulation of fat tissue dif‐fers from gender .The lesion of female patients are limited ,mainly involving the neck .The lesion of male patients are wide ,mainly involving the neck ,napex ,shoulder and back ,and upper chest .