中华心血管病杂志
中華心血管病雜誌
중화심혈관병잡지
Chinese Journal of Cardiology
2015年
9期
816-821
,共6页
桑大森%陶杰%宋达%黄科宇%许继波%董岩%陈朔华%吴寿岭
桑大森%陶傑%宋達%黃科宇%許繼波%董巖%陳朔華%吳壽嶺
상대삼%도걸%송체%황과우%허계파%동암%진삭화%오수령
健康行为%颈动脉狭窄%动脉粥样硬化
健康行為%頸動脈狹窄%動脈粥樣硬化
건강행위%경동맥협착%동맥죽양경화
Health behavior%Carotid stenosis%Atherosclerosis
目的 探讨心血管健康行为和因素对新发颈动脉斑块的影响.方法 分层单纯随机抽取开滦集团在职及离退休职工中年龄≥40岁、既往无卒中、短暂性脑缺血发作、心肌梗死者共5 852名,进行统一问卷调查、血液生化及颈动脉超声检查.纳入2010至2011年超声检查未检出颈动脉斑块且研究资料完整的研究对象2 372名.采用队列研究方法,观察2012至2013年体检时新发颈动脉斑块检出率.采用多因素logistic回归分析心血管健康行为和因素对新发颈动脉斑块的影响.结果 (1)共检出新发斑块359例,检出率为15.1％;具有0～1、2～3、4～5和6～7个理想心血管健康行为和因素研究对象的新发颈动脉斑块检出率分别为23.1％ (43/186)、17.5％(186/1 065)、12.4％(122/986)和5.9％ (8/135),差异有统计学意义(P <0.001).(2)多因素logistic回归分析显示:校正年龄、性别、高密度脂蛋白胆固醇、心率、高敏C反应蛋白后,与具有0～1个理想心血管健康行为和因素相比,具有4～5和6～7个理想心血管健康行为和因素是颈动脉斑块形成的保护因素,其OR(95％ CI)值分别为0.52(0.34 ～0.80)和0.28(0.12 ～0.64).结论 理想心血管健康行为和因素的数量越多,新发颈动脉斑块的检出率就越低.理想心血管健康行为和因素能预防颈动脉斑块的发生.
目的 探討心血管健康行為和因素對新髮頸動脈斑塊的影響.方法 分層單純隨機抽取開灤集糰在職及離退休職工中年齡≥40歲、既往無卒中、短暫性腦缺血髮作、心肌梗死者共5 852名,進行統一問捲調查、血液生化及頸動脈超聲檢查.納入2010至2011年超聲檢查未檢齣頸動脈斑塊且研究資料完整的研究對象2 372名.採用隊列研究方法,觀察2012至2013年體檢時新髮頸動脈斑塊檢齣率.採用多因素logistic迴歸分析心血管健康行為和因素對新髮頸動脈斑塊的影響.結果 (1)共檢齣新髮斑塊359例,檢齣率為15.1％;具有0～1、2～3、4～5和6～7箇理想心血管健康行為和因素研究對象的新髮頸動脈斑塊檢齣率分彆為23.1％ (43/186)、17.5％(186/1 065)、12.4％(122/986)和5.9％ (8/135),差異有統計學意義(P <0.001).(2)多因素logistic迴歸分析顯示:校正年齡、性彆、高密度脂蛋白膽固醇、心率、高敏C反應蛋白後,與具有0～1箇理想心血管健康行為和因素相比,具有4～5和6～7箇理想心血管健康行為和因素是頸動脈斑塊形成的保護因素,其OR(95％ CI)值分彆為0.52(0.34 ～0.80)和0.28(0.12 ～0.64).結論 理想心血管健康行為和因素的數量越多,新髮頸動脈斑塊的檢齣率就越低.理想心血管健康行為和因素能預防頸動脈斑塊的髮生.
목적 탐토심혈관건강행위화인소대신발경동맥반괴적영향.방법 분층단순수궤추취개란집단재직급리퇴휴직공중년령≥40세、기왕무졸중、단잠성뇌결혈발작、심기경사자공5 852명,진행통일문권조사、혈액생화급경동맥초성검사.납입2010지2011년초성검사미검출경동맥반괴차연구자료완정적연구대상2 372명.채용대렬연구방법,관찰2012지2013년체검시신발경동맥반괴검출솔.채용다인소logistic회귀분석심혈관건강행위화인소대신발경동맥반괴적영향.결과 (1)공검출신발반괴359례,검출솔위15.1％;구유0～1、2～3、4～5화6～7개이상심혈관건강행위화인소연구대상적신발경동맥반괴검출솔분별위23.1％ (43/186)、17.5％(186/1 065)、12.4％(122/986)화5.9％ (8/135),차이유통계학의의(P <0.001).(2)다인소logistic회귀분석현시:교정년령、성별、고밀도지단백담고순、심솔、고민C반응단백후,여구유0～1개이상심혈관건강행위화인소상비,구유4～5화6～7개이상심혈관건강행위화인소시경동맥반괴형성적보호인소,기OR(95％ CI)치분별위0.52(0.34 ～0.80)화0.28(0.12 ～0.64).결론 이상심혈관건강행위화인소적수량월다,신발경동맥반괴적검출솔취월저.이상심혈관건강행위화인소능예방경동맥반괴적발생.
Objective To explore the impact of ideal health behaviors on the newly developed carotid plaques.Methods A total of 5 852 employees (including retired employees from Tangshan Kailuan company) aged over 40 years were included in this study through stratified random sampling.Subjects with previous stroke,transient ischemic attack,myocardial infarction were excluded.Results from the unified questionnaire,blood biochemistry measurements and ultrasonography carotid artery measurements were analyzed.Present study analyzed the data from 2 372 participants without carotid plaques in 2010-2011 examinations.The newly developed carotid plaques in 2012-2013 health examinations were observed and multiple logistic regression analysis was used to explore the impact of ideal health behaviors and factors on the newly developed carotid plaques.Results (1) There were 359 subjects with newly developed carotid artery plaques among the 2 372 subjects (15.1％),prevalence rate was 23.1％ (43/186),17.5％ (186/1 065),12.4％ (122/986),5.9％ (8/135) in the groups with 0-1,2-3,4-5 and 6-7 components of ideal cardiovascular health behaviors and factors,respectively(P ＜ 0.001).(2) Multiple logistic regression analysis showed that after adjusting for age,gender,high density lipoprotein cholesterol,heart rate,and high sensitive c-reactive protein,compared to with 0-1 components of ideal cardiovascular health behaviors and factors,participants with 4-5 and 6-7 components of ideal cardiovascular health behaviors and factors were associated with reduced risk of the newly developed carotid plaques,the OR(95 ％ CI)values were 0.52 (0.34-0.80) and 0.28 (0.12-0.64),respectively.Conclusion Higher number of ideal cardiovascular health behaviors and factors is associated with lower incidence of newly developed carotid plaques.
