CAJ | 학술논문

胰腺癌是目前治疗最为棘手的消化道恶性肿瘤之一.研究结果表明,胰腺癌的发生、发展及转移与肿瘤的糖酵解途径关系紧密,大多数胰腺癌表现出升高的糖酵解表型,在一定程度上影响糖酵解途径,理论上可以影响肿瘤的能量代谢,而不影响正常细胞.因此,糖酵解途径可能成为治疗胰腺癌的新靶点.
이선암시목전치료최위극수적소화도악성종류지일.연구결과표명,이선암적발생、발전급전이여종류적당효해도경관계긴밀,대다수이선암표현출승고적당효해표형,재일정정도상영향당효해도경,이론상가이영향종류적능량대사,이불영향정상세포.인차,당효해도경가능성위치료이선암적신파점.
Pancreatic carcinoma is currently one of the most intractable malignant tumors of the digestive tract.Studies have found that the occurrence,progression and metastasis of pancreatic carcinoma are closely associated with the tumor's glycolytic pathway,most pancreatic carcinomas show the elevated glycolytic phenotype.To some extent,affecting the glycolytic pathway can influence the energy metabolism of the tumor without affecting the normal cells theoretically.Therefore,glycolytic pathway may become a new target for the treatment of pancreatic carcinoma.