中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
Chinese Journal of Practical Ophthalmology
2015年
8期
885-889
,共5页
阻塞性睡眠呼吸暂停综合征%视网膜神经纤维层厚度%青光眼%缺血性视神经病变
阻塞性睡眠呼吸暫停綜閤徵%視網膜神經纖維層厚度%青光眼%缺血性視神經病變
조새성수면호흡잠정종합정%시망막신경섬유층후도%청광안%결혈성시신경병변
Obstructive sleep apnea syndrome (OSAHS)%Retinal nerve fiber layer (RNFL)%Glaucoma%Ischemic optic neuropathy
目的 观察阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)与非阻塞性睡眠呼吸暂停综合征患者眼底神经纤维层厚度的变化.方法 临床病例对照研究.对2013年12月至2014年3月在重庆医科大学附属第一医院耳鼻喉科就诊的45例OSAHS患者同年龄、性别、无基础疾病的45例为对照组分别进睡眠呼吸监测、RNFL厚度、眼内压的测量,测量结果进行统计学分析.结果 OSAHS组患者与非OSAHS组的年龄、性别、眼压无统计学差异;OSAHS组较对照组的平均RNFL厚度(P＜0.01,t=2.8501)、鼻上RNFL厚度NS (P ＜0.001,t=3.4987)、鼻下RNFL厚度NI (P ＜0.05,t=2.5540)、颞上RNFL厚度TS (P ＜0.001,t=3.5546)、颞下RNFL厚度TI (P ＜0.05,t=2.5845)均明显变薄,差异有统计学意义.颞测RNFL厚度T(P ＞0.05,t=0.4174)、鼻测RNFL厚度N(P ＞0.05,t=1.9579)其差异无统计学意义.结论 OSAHS患者的平均、颞上、颞下、鼻上、鼻下方视网膜神经纤维层较非OSAHS患者变薄,OSAHS可能是青光眼、缺血性视神经病变的另一高危因素,应积极观察OSAHS患者的眼部表现.
目的 觀察阻塞性睡眠呼吸暫停綜閤徵(obstructive sleep apnea hypopnea syndrome,OSAHS)與非阻塞性睡眠呼吸暫停綜閤徵患者眼底神經纖維層厚度的變化.方法 臨床病例對照研究.對2013年12月至2014年3月在重慶醫科大學附屬第一醫院耳鼻喉科就診的45例OSAHS患者同年齡、性彆、無基礎疾病的45例為對照組分彆進睡眠呼吸鑑測、RNFL厚度、眼內壓的測量,測量結果進行統計學分析.結果 OSAHS組患者與非OSAHS組的年齡、性彆、眼壓無統計學差異;OSAHS組較對照組的平均RNFL厚度(P＜0.01,t=2.8501)、鼻上RNFL厚度NS (P ＜0.001,t=3.4987)、鼻下RNFL厚度NI (P ＜0.05,t=2.5540)、顳上RNFL厚度TS (P ＜0.001,t=3.5546)、顳下RNFL厚度TI (P ＜0.05,t=2.5845)均明顯變薄,差異有統計學意義.顳測RNFL厚度T(P ＞0.05,t=0.4174)、鼻測RNFL厚度N(P ＞0.05,t=1.9579)其差異無統計學意義.結論 OSAHS患者的平均、顳上、顳下、鼻上、鼻下方視網膜神經纖維層較非OSAHS患者變薄,OSAHS可能是青光眼、缺血性視神經病變的另一高危因素,應積極觀察OSAHS患者的眼部錶現.
목적 관찰조새성수면호흡잠정종합정(obstructive sleep apnea hypopnea syndrome,OSAHS)여비조새성수면호흡잠정종합정환자안저신경섬유층후도적변화.방법 림상병례대조연구.대2013년12월지2014년3월재중경의과대학부속제일의원이비후과취진적45례OSAHS환자동년령、성별、무기출질병적45례위대조조분별진수면호흡감측、RNFL후도、안내압적측량,측량결과진행통계학분석.결과 OSAHS조환자여비OSAHS조적년령、성별、안압무통계학차이;OSAHS조교대조조적평균RNFL후도(P＜0.01,t=2.8501)、비상RNFL후도NS (P ＜0.001,t=3.4987)、비하RNFL후도NI (P ＜0.05,t=2.5540)、섭상RNFL후도TS (P ＜0.001,t=3.5546)、섭하RNFL후도TI (P ＜0.05,t=2.5845)균명현변박,차이유통계학의의.섭측RNFL후도T(P ＞0.05,t=0.4174)、비측RNFL후도N(P ＞0.05,t=1.9579)기차이무통계학의의.결론 OSAHS환자적평균、섭상、섭하、비상、비하방시망막신경섬유층교비OSAHS환자변박,OSAHS가능시청광안、결혈성시신경병변적령일고위인소,응적겁관찰OSAHS환자적안부표현.
Objective To investigate changes in retinal nerve fiber layer (RNFL) in patients with obstructive sleep apnea syndrome (OSAHS).Methods In this study,45 patients with OSAHS were included based on apnea hypopnea index (AHI ≥5).The control group was matched for age,gender,best-corrected visual acuity and body mass index.Retinal nerve fiber layer (RNFL) parameters,intraocular pressure were compared between two groups.Results There was a significantly difference between groups in RNFL (average P ＜0.01;Nasal superior quadrant,NS P ＜0.01;Nasal inferior quadrant,NI P ＜0.05;Superior Temporal quadrant,TS P ＜0.01;temporal inferior quadrant,TI P ＜0.05),and there was no significantly difference between groups in Temporal quadrant and Nasal quadrant.No significantly difference in best-corrected visual acuity,intraocular pressure,age,and gender between two groups.Conclusions The retinal nerve fiber layer of OSAHS (average,nasal superior quadrant,nasal inferior quadrant,superior temporal quadrant,and temporal inferior quadrant) is thinner than those of non-OSAHS.This may be another high risk factor for glaucoma or Non-arteritic ischemic optic neuropathy.
