CAJ | 학술논문

目的：优化无糖润肺颗粒剂的醇提取生产工艺。方法采用3个不同比例的乙醇水作溶剂，选择4因素3水平正交表L9（34）进行试验，对处方中9味中药的醇溶性成分进行提取，以黄芩苷含量和干浸膏得率2者加权之和为定量指标，对影响醇提取效率的4个因素3个水平进行考察。结果醇溶性成分提取最优条件为：取9味中药先用10倍量70％乙醇浸泡45 min，再加热回流提取3次，每次1.5h。结论本法可最大限度提取处方中9味中药的醇溶性成分，可作为润肺颗粒剂的醇提取生产工艺。
목적：우화무당윤폐과립제적순제취생산공예。방법채용3개불동비례적을순수작용제，선택4인소3수평정교표L9（34）진행시험，대처방중9미중약적순용성성분진행제취，이황금감함량화간침고득솔2자가권지화위정량지표，대영향순제취효솔적4개인소3개수평진행고찰。결과순용성성분제취최우조건위：취9미중약선용10배량70％을순침포45 min，재가열회류제취3차，매차1.5h。결론본법가최대한도제취처방중9미중약적순용성성분，가작위윤폐과립제적순제취생산공예。
Objective To optimize ethonal extraction technology for no sugar runfei granules.Methods Ethanol was used as a solvent to extract the ethanol dissolvable ingredients in 9 kinds of medicinal materials.The formula L9 (34 ) table was used to examine the effects of 4 factors and 3 levels.The weighted sum of baicalin content and the dried extract quantity was used as quantitative index.Results The maximize optimize condition for extraction of ethanol dissolvable ingredients was as follows:9 kinds of medicinal materials, add of 10-fold 70% ethanol solution, soaked for 45 min, and extracted by heating reflux for 3 times,1.5 h each time.Conclusion The method can maximize extraction of ethanol dissolvable effective ingredents in 9 kinds of medicinal materials and can be used as ethonal extraction technologgary of no sugar runfei granules.