CAJ | 학술논문

目的探讨甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)淋巴结转移的高危因素及预防性颈部淋巴结清扫术的必要性.方法回顾性分析天津市肿瘤医院2013年1月至2014年1月收治的1 990例初诊为PTMC患者的临床资料.结果单因素分析PTMC淋巴结转移与患者性别、年龄、腺外侵犯、双侧肿瘤、特殊类型、多灶性相关(均P ＜0.05).多因素分析PTMC淋巴结转移与患者性别、年龄、肿瘤大小、腺外侵犯、双侧肿瘤、多灶性相关.配对分析显示PTMC特殊类型最大径＞0.5 cm较最大径＜0.5 cm更具淋巴结转移倾向.无单个高危因素患者淋巴结转移率为8.13％,多因素分析无高危因素者淋巴结转移率为6.80％.结论 PTMC颈部淋巴结转移与患者性别、年龄、肿瘤大小、侵出腺叶、双侧肿瘤、多灶性相关.高危因素PTMC患者可进行预防性淋巴结清扫,非高危因素患者不建议进行预防性淋巴结清扫术.
목적 탐토갑상선미소유두상암(papillary thyroid microcarcinoma,PTMC)림파결전이적고위인소급예방성경부림파결청소술적필요성.방법 회고성분석천진시종류의원2013년1월지2014년1월수치적1 990례초진위PTMC환자적림상자료.결과 단인소분석PTMC림파결전이여환자성별、년령、선외침범、쌍측종류、특수류형、다조성상관(균P ＜0.05).다인소분석PTMC림파결전이여환자성별、년령、종류대소、선외침범、쌍측종류、다조성상관.배대분석현시PTMC특수류형최대경＞0.5 cm교최대경＜0.5 cm경구림파결전이경향.무단개고위인소환자림파결전이솔위8.13％,다인소분석무고위인소자림파결전이솔위6.80％.결론 PTMC경부림파결전이여환자성별、년령、종류대소、침출선협、쌍측종류、다조성상관.고위인소PTMC환자가진행예방성림파결청소,비고위인소환자불건의진행예방성림파결청소술.
Objective To study risk factors of neck lymph node metastasis in papillary thyroid microcarcinoma (PTMC) patients.Methods The clinical data of 1 990 PTMC patients admitted in Tianjin Tumor Hospital from Jan 2013 to Jan 2014 was retrospectively analyzed.Results The univariate analysis results showed that gender,age,extra glandular invasion,bilateral thyroid cancer,the special cancer type,and multifocal cancer are associated with high lymph node metastasis rate.Multivariate analysis showed that patient's sex,age,tumor size,extra glandular invasion,bilateral thyroid tumors,multifocal are associated with the lymph node metastasis.Conclusions In PTMC,neck lymph node metastasis was related with the risk factors of patient's gender,age,tumor size,tumor invasion,bilateral lesion,muhifocal disease.Prophylactic lymph node dissection may be justified in PTMC patients with high risk factors.