CAJ | 학술논문

目的：探讨18F-脱氧葡萄糖（18F-FDG）PET/CT在胰腺肿瘤鉴别诊断与分期中的作用和价值。方法：回顾性分析治疗前拟诊“胰腺肿瘤”，并在检查后4周内获得病理学结果的66例患者的18F-FDG PET/CT检查资料。结果：恶性组病灶最大标准摄取值(SUVmax)为2.2~21.6(平均6.45±3.44)，低度恶性组病灶SUVmax为2.4~12.8(平均7.04±3.65)，良性组病灶SUVmax为2.0~2.6(平均2.30±0.29)，其中恶性组与良性组、低度恶性组与良性组的SUVmax比较差异均具有统计学意义(P值分别为0.02及0.003)，而恶性组与低度恶性组SUVmax比较差异无统计学意义(P=0.662)。PET/CT对N分期的判断欠满意，但21.0%(13/62)病例因PET/CT发现远处转移而改变了治疗决策。结论：18F-FDG PET/CT有助于胰腺占位的良恶性鉴别，虽然在胰腺癌区域淋巴结的检出和判断方面不具备显著优势，但对M分期的准确评估使相当一部分患者获得了最优化的治疗。
목적：탐토18F-탈양포도당（18F-FDG）PET/CT재이선종류감별진단여분기중적작용화개치。방법：회고성분석치료전의진“이선종류”，병재검사후4주내획득병이학결과적66례환자적18F-FDG PET/CT검사자료。결과：악성조병조최대표준섭취치(SUVmax)위2.2~21.6(평균6.45±3.44)，저도악성조병조SUVmax위2.4~12.8(평균7.04±3.65)，량성조병조SUVmax위2.0~2.6(평균2.30±0.29)，기중악성조여량성조、저도악성조여량성조적SUVmax비교차이균구유통계학의의(P치분별위0.02급0.003)，이악성조여저도악성조SUVmax비교차이무통계학의의(P=0.662)。PET/CT대N분기적판단흠만의，단21.0%(13/62)병례인PET/CT발현원처전이이개변료치료결책。결론：18F-FDG PET/CT유조우이선점위적량악성감별，수연재이선암구역림파결적검출화판단방면불구비현저우세，단대M분기적준학평고사상당일부분환자획득료최우화적치료。
Objective:To evaluate the value of18F-lfuorodeoxyglucose (18F-FDG) PET/CT in differential diagnosis and staging of pancreatic neoplasms.Methods:A total of 66 patients who underwent18F-FDG PET/CT examination for suspected pancreatic neoplasms were confirmed with pathology.Results:The maximal standardized uptake value (SUVmax) in malignant group was 2.2-21.6 (6.45±3.44) and in low-grade malignant group was 2.4-12.8(7.04±3.65), and in benign group was 2.0-2.6 (2.30±0.29). The SUVmax was signiifcantly different between benign group and malignant group (P=0.02) or low-grade malignant group(P=0.003). There was no signiifcant difference in SUVmax between malignant group and low-grade malignant group. PET/CT changed 21% patients’ therapy plan.Conclusion:PET/CT is a useful tool in the differential diagnosis of benign from malignant pancreatic diseases, and helps to make a more accurate clinical decision.